SNTG2, syntrophin gamma 2

SNTG2, syntrophin gamma 2

• This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (gamma-2-syntrophin, syntrophin-5, G2SYN, SYN5,)
• NCBI Gene ID: 54221
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NY99
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

syntrophin gamma 2 interacts with:

• epithelial stromal interaction 1
  HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
  membrane palmitoylated protein 5
  mirror-image polydactyly 1
  NSFL1 cofactor
  ring finger protein 31
  selenoprotein S
  valosin containing protein interacting protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.