SEMA5B, semaphorin 5B

SEMA5B, semaphorin 5B

• This gene encodes a member of the semaphorin protein family which regulates axon growth during development of the nervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through which semaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. The protein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

• Gene Synonyms (semaphorin-5B, sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B, SEMAG, SemG,)
• NCBI Gene ID: 54437
• Species: Homo sapiens (Human)
• UNIPROT ID#>>C9JKR3
  UNIPROT ID#>>Q9P283
  UNIPROT ID#>>B7Z2B3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

semaphorin 5B interacts with:

• family with sequence similarity 118 member B
  mitochondrial ribosomal protein L44

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.