CROT, carnitine O-octanoyltransferase

CROT, carnitine O-octanoyltransferase

• This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]

• Gene Synonyms (peroxisomal carnitine O-octanoyltransferase, peroxisomal carnitine acyltransferase, COT,)
• NCBI Gene ID: 54677
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKG9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carnitine O-octanoyltransferase interacts with:

• eukaryotic translation initiation factor 2 alpha kinase 4
  GATA zinc finger domain containing 2B
  integrator complex subunit 14
  kelch domain containing 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.