CHST12, carbohydrate sulfotransferase 12

CHST12, carbohydrate sulfotransferase 12

• The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. Alternatively spliced transcript variants differing only in their 5' UTRs have been found for this gene. [provided by RefSeq, Aug 2011]

• Gene Synonyms (C4S-2, C4ST-2, C4ST2, carbohydrate sulfotransferase 12, carbohydrate (chondroitin 4) sulfotransferase 12, chondroitin 4-O-sulfotransferase 2, chondroitin 4-sulfotransferase 2, sulfotransferase Hlo,)
• NCBI Gene ID: 55501
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NRB3
  UNIPROT ID#>>A0A024R860
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carbohydrate sulfotransferase 12 interacts with:

• 5-hydroxytryptamine receptor 3C
  ATP23 metallopeptidase and ATP synthase assembly factor homolog
  chromobox 8
  dipeptidase 2
  lysozyme like 1
  metallophosphoesterase 1
  mitotic spindle organizing protein 2
  UDP-glucose glycoprotein glucosyltransferase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.