PSD, pleckstrin and Sec7 domain containing

PSD, pleckstrin and Sec7 domain containing

• This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

• Gene Synonyms (PH and SEC7 domain-containing protein 1, exchange factor for ADP-ribosylation factor guanine nucleotide factor 6, exchange factor for ARF6, exchange factor for ARF6 A, pleckstrin homology and SEC7 domain-containing protein 1, pleckstrin-Sec7 domains-containing, EFA6, EFA6A, PSD1, TYL,)
• NCBI Gene ID: 5662
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86YI3
  UNIPROT ID#>>A5PKW4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

pleckstrin and Sec7 domain containing interacts with:

• G protein subunit beta 5
  glia maturation factor gamma
  hexosaminidase D
  RAB40C, member RAS oncogene family
  trafficking regulator and scaffold protein tamalin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.