UVSSA, UV stimulated scaffold protein A

UVSSA, UV stimulated scaffold protein A

• The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (KIAA1530, UVSS3, UV-stimulated scaffold protein A,)
• NCBI Gene ID: 57654
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q69YU2
  UNIPROT ID#>>Q2YD98
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

UV stimulated scaffold protein A interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.