KMT2C, lysine methyltransferase 2C

KMT2C, lysine methyltransferase 2C

• This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]

• Gene Synonyms (histone-lysine N-methyltransferase 2C, ALR-like protein, histone-lysine N-methyltransferase MLL3, histone-lysine N-methyltransferase, H3 lysine-4 specific, homologous to ALR protein, lysine (K)-specific methyltransferase 2C, myeloid/lymphoid or mixed-lineage leukemia protein 3, HALR, KLEFS2, MLL3,)
• NCBI Gene ID: 58508
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NEZ4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysine methyltransferase 2C interacts with:

• ASXL transcriptional regulator 1
  ASXL transcriptional regulator 3
  cell division cycle 73
  dpy-30 histone methyltransferase complex regulatory subunit
  H3 clustered histone 14
  lysine demethylase 1B
  PAXIP1 associated glutamate rich protein 1
  ring finger protein 123
  WD repeat domain 82

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.