REV3L, REV3 like, DNA directed polymerase zeta catalytic subunit

REV3L, REV3 like, DNA directed polymerase zeta catalytic subunit

• The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]

• Gene Synonyms (DNA polymerase zeta catalytic subunit, REV3-like, polymerase (DNA directed), zeta, catalytic subunit, Rev-3, yeast, homolog-like (polymerase, DNA, zeta), POLZ, REV3,)
• NCBI Gene ID: 5980
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UG47
  UNIPROT ID#>>O60673
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

REV3 like, DNA directed polymerase zeta catalytic subunit interacts with:

• ATPase family AAA domain containing 1
  CASP8 and FADD like apoptosis regulator
  checkpoint kinase 2
  chromodomain Y-linked 1
  COPI coat complex subunit zeta 1
  cysteine sulfinic acid decarboxylase
  family with sequence similarity 107 member A
  histone deacetylase 4
  lemur tyrosine kinase 3
  MAD2 mitotic arrest deficient-like 2
  mitotic arrest deficient 2 like 2
  regulatory factor X associated protein
  REV1 DNA directed polymerase
  ribonucleotide reductase catalytic subunit M1
  ribosomal protein L14
  ring finger protein 123
  serine/threonine kinase 17b
  solute carrier family 16 member 10
  suppressor of cancer cell invasion
  telomeric repeat binding factor 2
  thioredoxin
  TNFAIP3 interacting protein 2
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.