MRPL17, mitochondrial ribosomal protein L17

MRPL17, mitochondrial ribosomal protein L17

• Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (39S ribosomal protein L17, mitochondrial, LYST-interacting protein 2, LYST-interacting protein LIP2, mitochondrial large ribosomal subunit protein bL17m, L17mt, LIP2, MRP-L17, MRP-L26, RPL17L, RPML26,)
• NCBI Gene ID: 63875
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NRX2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitochondrial ribosomal protein L17 interacts with:

• mitochondrial ribosomal protein L1
  mitochondrial ribosomal protein L10
  mitochondrial ribosomal protein L41
  mitochondrial ribosomal protein L9
  ring finger and SPRY domain containing 1
  ubiquitin domain containing 2
  ubiquitin like modifier activating enzyme 5
  zinc finger protein 324B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.