CDH23, cadherin related 23

CDH23, cadherin related 23

• This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]

• Gene Synonyms (cadherin-23, cadherin-like 23, cadherin-related family member 23, otocadherin, CDHR23, PITA5, USH1D,)
• NCBI Gene ID: 64072
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A5D6V9
  UNIPROT ID#>>A0A087WYR8
  UNIPROT ID#>>Q6P152
  UNIPROT ID#>>Q9H251
  UNIPROT ID#>>Q8N5B3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cadherin related 23 interacts with:

• nucleoredoxin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.