CRTC3, CREB regulated transcription coactivator 3

CRTC3, CREB regulated transcription coactivator 3

• This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

• Gene Synonyms (CREB-regulated transcription coactivator 3, transducer of regulated CREB protein 3, transducer of regulated cAMP response element-binding protein (CREB) 3, TORC-3, TORC3,)
• NCBI Gene ID: 64784
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TEF4
  UNIPROT ID#>>Q6UUV7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CREB regulated transcription coactivator 3 interacts with:

• carbonic anhydrase 13
  charged multivesicular body protein 4B
  egl-9 family hypoxia inducible factor 3
  NEDD1 gamma-tubulin ring complex targeting factor
  Sec24 related gene family, member C (S. cerevisiae)

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.