SLC8A3, solute carrier family 8 member A3

SLC8A3, solute carrier family 8 member A3

• This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013]

• Gene Synonyms (sodium/calcium exchanger 3, Na(+)/Ca(2+)-exchange protein 3, sodium/calcium exchanger SLC8A3, solute carrier family 8 (sodium/calcium exchanger), member 3, NCX3,)
• NCBI Gene ID: 6547
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P57103
  UNIPROT ID#>>B3KU59
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 8 member A3 interacts with:

• chondroitin sulfate N-acetylgalactosaminyltransferase 2
  ER membrane protein complex subunit 7
  receptor accessory protein 4
  signal peptide peptidase like 2B
  transmembrane protein 43
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.