SMPD2, sphingomyelin phosphodiesterase 2

SMPD2, sphingomyelin phosphodiesterase 2

• This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009]

• Gene Synonyms (sphingomyelin phosphodiesterase 2, N-SMase, lyso-PAF-PLC, lyso-platelet-activating factor-phospholipase C, neutral sphingomyelinase, ISC1, NSMASE, NSMASE1,)
• NCBI Gene ID: 6610
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60906
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sphingomyelin phosphodiesterase 2 interacts with:

• ADP ribosylation factor interacting protein 1
  anaphase promoting complex subunit 10
  coenzyme Q8A
  family with sequence similarity 189 member B
  leucine rich repeat transmembrane neuronal 1
  NDRG family member 4
  OTU deubiquitinase with linear linkage specificity like
  phosphatidylinositol transfer protein cytoplasmic 1
  plasmalemma vesicle associated protein
  progesterone receptor membrane component 2
  protocadherin alpha 3
  protocadherin alpha subfamily C, 2
  protocadherin beta 16
  protocadherin beta 7
  protocadherin gamma subfamily A, 5
  protocadherin gamma subfamily B, 4
  solute carrier family 7 member 8
  SRP receptor subunit beta
  steroidogenic acute regulatory protein
  transmembrane p24 trafficking protein 6
  transmembrane protein 14B
  transmembrane protein 167B
  transmembrane protein 30A
  transmembrane protein 31
  zinc and ring finger 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.