ST13, ST13 Hsp70 interacting protein

ST13, ST13 Hsp70 interacting protein

• The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

• Gene Synonyms (hsc70-interacting protein, Hsp70-interacting protein, aging-associated protein 2, heat shock 70kD protein binding protein, progesterone receptor-associated p48 protein, putative tumor suppressor ST13, renal carcinoma antigen NY-REN-33, suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein), suppression of tumorigenicity 13 protein, testis secretory sperm-binding protein Li 233m, AAG2, FAM10A1, FAM10A4, HIP, HOP, HSPABP, HSPABP1, P48, PRO0786, SNC6,)
• NCBI Gene ID: 6767
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4E0U6
  UNIPROT ID#>>A0A140VKA6
  UNIPROT ID#>>Q0IJ56
  UNIPROT ID#>>P50502
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ST13 Hsp70 interacting protein interacts with:

• anti-silencing function 1A histone chaperone
  BAG cochaperone 3
  CD101 molecule
  chloride intracellular channel 4
  chymotrypsin C
  copine 1
  cullin 2
  C-X-C motif chemokine receptor 4
  destrin, actin depolymerizing factor
  Fas associated factor 1
  HEAT repeat containing 3
  HEXIM P-TEFb complex subunit 1
  interferon induced transmembrane protein 3
  kinase suppressor of ras 1
  nuclear receptor subfamily 2 group C member 2
  olfactomedin 2
  poly(A) binding protein nuclear 1
  protein kinase C and casein kinase substrate in neurons 2
  protein kinase C and casein kinase substrate in neurons 3
  PTEN induced kinase 1
  SUB1 regulator of transcription
  transthyretin
  U2 small nuclear RNA auxiliary factor 2
  ubiquilin 2
  valosin containing protein
  vav guanine nucleotide exchange factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.