TBXAS1, thromboxane A synthase 1

TBXAS1, thromboxane A synthase 1

• This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

• Gene Synonyms (thromboxane-A synthase, TXA synthase, cytochrome P450 5A1, cytochrome P450, family 5, subfamily A, polypeptide 1, platelet, cytochrome P450, subfamily V, thromboxane A synthase 1 (platelet), BDPLT14, CYP5, CYP5A1, GHOSAL, THAS, TS, TXAS, TXS,)
• NCBI Gene ID: 6916
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DVP1
  UNIPROT ID#>>Q53F23
  UNIPROT ID#>>A0A0C4DH47
  UNIPROT ID#>>A0A0A0MSK3
  UNIPROT ID#>>P24557
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

thromboxane A synthase 1 interacts with:

• ubiquitin C

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