TSPAN8, tetraspanin 8

TSPAN8, tetraspanin 8

• The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (tetraspanin-8, transmembrane 4 superfamily member 3, tspan-8, tumor-associated antigen CO-029, CO-029, TM4SF3,)
• NCBI Gene ID: 7103
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P19075
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tetraspanin 8 interacts with:

• solute carrier family 38 member 7
  translocase of inner mitochondrial membrane 23

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.