ZFX, zinc finger protein X-linked

ZFX, zinc finger protein X-linked

• This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2010]

• Gene Synonyms (zinc finger X-chromosomal protein, X-linked zinc finger protein, ZNF926,)
• NCBI Gene ID: 7543
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P17010
  UNIPROT ID#>>Q8WXB7
  UNIPROT ID#>>A0A024RC04
  UNIPROT ID#>>Q59EB9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger protein X-linked interacts with:

• cell division cycle 23
  centromere protein Q
  H4 clustered histone 1
  tripartite motif containing 25
  vir like m6A methyltransferase associated
  zinc finger protein Y-linked

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