CENPU, centromere protein U

CENPU, centromere protein U

• The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (centromere protein U, KSHV latent nuclear antigen interacting protein 1, MLF1 interacting protein, centromere protein of 50 kDa, interphase centromere complex protein 24, polo-box-interacting protein 1, CENP50, CENPU50, KLIP1, MLF1IP, PBIP1,)
• NCBI Gene ID: 79682
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q71F23
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

centromere protein U interacts with:

• centromere protein L
  centromere protein P
  centromere protein Q
  centromere protein S
  centromere protein T
  centromere protein X
  lysine rich nucleolar protein 1
  microtubule interacting and trafficking domain containing 1
  SPT2 chromatin protein domain containing 1
  tubulin beta 2B class IIb
  zinc finger MYM-type containing 1
  zinc finger protein 512

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