PDGFD, platelet derived growth factor D

PDGFD, platelet derived growth factor D

• The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (platelet-derived growth factor D, PDGF-D, iris-expressed growth factor, spinal cord-derived growth factor B, IEGF, MSTP036, SCDGF-B, SCDGFB,)
• NCBI Gene ID: 80310
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9GZP0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

platelet derived growth factor D interacts with:

• dynactin subunit 5
  neuralized E3 ubiquitin protein ligase 4
  POTE ankyrin domain family member E
  SEH1 like nucleoporin
  ubiquitin protein ligase E3 component n-recognin 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.