AP3B2, adaptor related protein complex 3 subunit beta 2

AP3B2, adaptor related protein complex 3 subunit beta 2

• Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017]

• Gene Synonyms (AP-3 complex subunit beta-2, Neuronal adaptin-like protein, beta-subunit, adaptor protein complex AP-3 subunit beta-2, adaptor related protein complex 3 beta 2 subunit, beta-3B-adaptin, clathrin assembly protein complex 3 beta-2 large chain, neuron-specific vesicle coat protein beta-NAP, EIEE48, NAPTB,)
• NCBI Gene ID: 8120
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13367
  UNIPROT ID#>>F5GYB0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

adaptor related protein complex 3 subunit beta 2 interacts with:

• adaptor related protein complex 3 subunit delta 1
  adaptor related protein complex 3 subunit mu 1
  ArfGAP with dual PH domains 1
  dystrobrevin binding protein 1
  pleckstrin homology domain containing A4
  RUN and FYVE domain containing 1

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