FBXO38, F-box protein 38

FBXO38, F-box protein 38

• This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

• Gene Synonyms (F-box only protein 38, modulator of KLF7 activity homolog, Fbx38, HMN2D, MOKA, SP329,)
• NCBI Gene ID: 81545
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6PIJ6
  UNIPROT ID#>>Q6AZE0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

F-box protein 38 interacts with:

• AT-rich interaction domain 5B
  chromatin licensing and DNA replication factor 1
  coiled-coil domain containing 77
  cyclin L2
  death effector domain containing 2
  family with sequence similarity 172 member A
  jumonji domain containing 1C
  kinesin family member 18A
  lin-52 DREAM MuvB core complex component
  lin-9 DREAM MuvB core complex component
  NODAL modulator 2
  nudix hydrolase 16 like 1
  polycomb group ring finger 1
  POM121 transmembrane nucleoporin C
  programmed cell death 2 like
  proline rich coiled-coil 2B
  ribonucleoprotein, PTB binding 1
  ring finger protein 169
  shugoshin 2
  TOPBP1 interacting checkpoint and replication regulator
  transcriptional adaptor 2B
  zinc finger C3H1-type containing
  zinc finger protein 362
  zinc finger protein 644
  zinc finger protein 780A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.