FZD4, frizzled class receptor 4

FZD4, frizzled class receptor 4

• This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]

• Gene Synonyms (frizzled-4, WNT receptor frizzled-4, frizzled 4, seven transmembrane spanning receptor, frizzled family receptor 4, frizzled homolog 4, CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4,)
• NCBI Gene ID: 8322
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9ULV1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

frizzled class receptor 4 interacts with:

• dishevelled segment polarity protein 3
  membrane associated guanylate kinase, WW and PDZ domain containing 3
  PDZ domain containing ring finger 3
  zinc and ring finger 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.