FZD8, frizzled class receptor 8

FZD8, frizzled class receptor 8

• This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (frizzled-8, frizzled 8, seven transmembrane spanning receptor, frizzled family receptor 8, frizzled homolog 8, FZ-8, hFZ8,)
• NCBI Gene ID: 8325
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H461
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

frizzled class receptor 8 interacts with:

• epsin 1
  golgi associated PDZ and coiled-coil motif containing
  inositol-pentakisphosphate 2-kinase
  ring finger protein 43
  uroplakin 1A
  WT1 associated protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.