RAD54L, RAD54 like

RAD54L, RAD54 like

• The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]

• Gene Synonyms (DNA repair and recombination protein RAD54-like, RAD54 homolog, HR54, RAD54A, hHR54, hRAD54,)
• NCBI Gene ID: 8438
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92698
  UNIPROT ID#>>A8K996
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RAD54 like interacts with:

• HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  N-terminal glutamine amidase 1
  small glutamine rich tetratricopeptide repeat containing beta
  tectonin beta-propeller repeat containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.