CGNL1, cingulin like 1

CGNL1, cingulin like 1

• This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011]

• Gene Synonyms (cingulin-like protein 1, junction-associated coiled-coil protein, paracingulin, JACOP, PCING,)
• NCBI Gene ID: 84952
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q0VF96
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cingulin like 1 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.