EDF1, endothelial differentiation related factor 1

EDF1, endothelial differentiation related factor 1

• This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Gene Synonyms (endothelial differentiation-related factor 1, multiprotein bridging factor 1, CFAP280, EDF-1, MBF1,)
• NCBI Gene ID: 8721
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60869
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

endothelial differentiation related factor 1 interacts with:

• autophagy related 16 like 1
  BICD cargo adaptor 2
  developmental pluripotency associated 4
  DExH-box helicase 29
  elongation factor Tu GTP binding domain containing 2
  HEXIM P-TEFb complex subunit 1
  mab-21 like 2
  Nanog homeobox
  nuclear receptor subfamily 1 group H member 3
  ribonuclease H2 subunit A
  ring finger and CCCH-type domains 1
  vir like m6A methyltransferase associated
  WW domain containing E3 ubiquitin protein ligase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.