KYNU, kynureninase

KYNU, kynureninase

• Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

• Gene Synonyms (kynureninase, L-kynurenine hydrolase, KYNUU, VCRL2,)
• NCBI Gene ID: 8942
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q16719
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

kynureninase interacts with:

• anterior gradient 2, protein disulphide isomerase family member
  BRCA2 and CDKN1A interacting protein
  cancer/testis antigen 55
  carnosine dipeptidase 2
  chromosome 11 open reading frame 58
  cysteine and histidine rich domain containing 1
  destrin, actin depolymerizing factor
  guanine deaminase
  lactate dehydrogenase A like 6B
  mediator of cell motility 1
  mitochondrial coiled-coil domain 1
  myozenin 3
  N-acetylglucosamine kinase
  N-myc downstream regulated 1
  nuclear RNA export factor 1
  nucleoporin 210
  PALM2 and AKAP2 fusion
  phosphoserine aminotransferase 1
  protein phosphatase 4 regulatory subunit 3B
  Ras association domain family member 3
  SEC23 interacting protein
  sirtuin 1
  SSU72 homolog, RNA polymerase II CTD phosphatase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.