CCNB2, cyclin B2

CCNB2, cyclin B2

• Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]

• Gene Synonyms (G2/mitotic-specific cyclin-B2, HsT17299,)
• NCBI Gene ID: 9133
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95067
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cyclin B2 interacts with:

• centrosomal protein 128
  coiled-coil domain containing 14
  cyclin-dependent kinase 1
  diaphanous related formin 3
  family with sequence similarity 234 member B
  GDP-mannose pyrophosphorylase B
  growth hormone inducible transmembrane protein
  heterogeneous nuclear ribonucleoprotein L like
  keratin 73
  limb development membrane protein 1 like
  mindbomb E3 ubiquitin protein ligase 1
  ninein
  PAX interacting protein 1
  PDS5 cohesin associated factor A
  pleckstrin homology domain containing A4
  ribonuclease H2 subunit C
  SR-related CTD associated factor 4
  TSPY like 2
  VAMP associated protein A
  VAMP associated protein B and C
  WD repeat and FYVE domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.