PIGM, phosphatidylinositol glycan anchor biosynthesis class M

PIGM, phosphatidylinositol glycan anchor biosynthesis class M

• This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]

• Gene Synonyms (GPI mannosyltransferase 1, DPM:GlcN-(acyl-)PI mannosyltransferase, GPI mannosyltransferase I, PIG-M mannosyltransferase, dol-P-Man dependent GPI mannosyltransferase, phosphatidylinositol-glycan biosynthesis class M protein, GPI-MT-I,)
• NCBI Gene ID: 93183
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H3S5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol glycan anchor biosynthesis class M interacts with:

• 5-hydroxytryptamine receptor 3C
  adhesion G protein-coupled receptor G5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.