RASAL2, RAS protein activator like 2

RASAL2, RAS protein activator like 2

• This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ras GTPase-activating protein nGAP, RASAL2/ACVR1 fusion, Ras protein activator like 1, NGAP,)
• NCBI Gene ID: 9462
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UJF2
  UNIPROT ID#>>A8K2P3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RAS protein activator like 2 interacts with:

• ankyrin repeat domain 28
  ankyrin repeat domain 34A
  ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
  calmodulin regulated spectrin associated protein family member 2
  centrosomal protein 128
  centrosomal protein 78
  chibby family member 1, beta catenin antagonist
  cingulin
  DENN domain containing 1A
  DENN domain containing 4C
  eukaryotic translation initiation factor 4E family member 2
  family with sequence similarity 110 member B
  family with sequence similarity 53 member C
  GRB10 interacting GYF protein 1
  GRB10 interacting GYF protein 2
  histone deacetylase 4
  inositol polyphosphate-5-phosphatase E
  kinesin family member 13B
  kinesin family member 1C
  large tumor suppressor kinase 2
  leucine rich repeat and fibronectin type III domain containing 1
  LIM domain and actin binding 1
  lipin 3
  MAPK associated protein 1
  matrix Gla protein
  microtubule associated serine/threonine kinase 3
  mitogen-activated protein kinase kinase kinase 21
  NAD kinase
  pleckstrin homology domain containing A7
  pleckstrin homology like domain family B member 2
  potassium channel tetramerization domain containing 3
  protein kinase C, iota
  protein phosphatase, Mg2+/Mn2+ dependent 1H
  Ral GEF with PH domain and SH3 binding motif 2
  serine and arginine rich splicing factor 12
  SH3 and PX domains 2A
  SH3 domain containing kinase binding protein 1
  signal induced proliferation associated 1 like 1
  SLIT-ROBO Rho GTPase activating protein 2
  synapse defective Rho GTPase homolog 1
  testis associated actin remodelling kinase 2
  transmembrane protein 17
  ubiquitin specific peptidase 21
  USH1 protein network component harmonin binding protein 1
  vir like m6A methyltransferase associated
  zinc finger and BTB domain containing 21
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.