OSBPL2, oxysterol binding protein like 2

OSBPL2, oxysterol binding protein like 2

• This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]

• Gene Synonyms (oxysterol-binding protein-related protein 2, OSBP-related protein 2, DFNA67, DNFA67, ORP-2, ORP2,)
• NCBI Gene ID: 9885
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E7ET92
  UNIPROT ID#>>Q9H1P3
  UNIPROT ID#>>B4DKJ8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

oxysterol binding protein like 2 interacts with:

• baculoviral IAP repeat containing 6
  DENN/MADD domain containing 6A
  OTU deubiquitinase with linear linkage specificity like
  small glutamine rich tetratricopeptide repeat containing beta
  spire type actin nucleation factor 2
  vesicle-associated membrane protein 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.