SV2B, synaptic vesicle glycoprotein 2B

SV2B, synaptic vesicle glycoprotein 2B

• This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. [provided by RefSeq, Sep 2016]

• Gene Synonyms (synaptic vesicle glycoprotein 2B, synaptic vesicle protein 2B homolog, HsT19680,)
• NCBI Gene ID: 9899
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7L1I2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

synaptic vesicle glycoprotein 2B interacts with:

• chromosome 6 open reading frame 15
  heat shock transcription factor Y-linked 1
  vir like m6A methyltransferase associated
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.