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Copyright

Promega Copyright Statement

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Trademarks

Trademarks referenced herein are either registered trademarks or trademarks of Promega Corporation in the U.S. and/or other countries. The names of actual companies and products mentioned herein and/or third party trademarks, trade names and logos contained herein may be the trademarks of their respective owners. Any rights not expressly granted herein are reserved.

Promega Web Site Disclaimers

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Links to Other Web Sites

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Promega Copyright Statement

Limited Use Label Licenses

ADCC Bioassay Effector Cells Limited Use Label License

ADCC Reporter Bioassay, Core Kits
ADCC Reporter Bioassay, Complete Kit (WIL2-S)
ADCC Reporter Bioassay, Complete Kit (Raji)

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the recipient with a full refund.

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Effector Cells or the luciferase gene stably transfected within the Effector Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all determinations of luminescence activity of this product, or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

ADCC Bioassay Target Cells Limited Use Label License

ADCC Reporter Bioassay, Complete Kit (WIL2-S)
ADCC Reporter Bioassay, Target Kit (WIL2-S)
ADCC Bioassay Target Cells (WIL2-S)
ADCC Reporter Bioassay, Complete Kit (Raji)
ADCC Reporter Bioassay, Target Kit (Raji)
ADCC Bioassay Target Cells (Raji)

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the Target Cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product, or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

ADCC Bioassay Cell-Propagation Model Limited Use Label License

ADCC Bioassay Effector Cells, Propagation Model

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) drug discovery and development of biologic drugs, (3) quality assurance testing of biologic drugs, and (4) product release assays for biologic drugs. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to modify, derivatize, genetically engineer or otherwise create variations of the Effector Cells or the luciferase gene stably transfected within the Effector Cells, except that recipient may propagate and store Effector Cells for use in Antibody-Dependent Cell-Mediated Cytotoxicity assays. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all determinations of luminescence activity of this product, or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

General Bioassay Limited Use Label License
(using Bio-Glo™ Luciferase Assay System)

4-1BB Blockade Bioassay
aAPC/Raji Cells
CD28 Bioassay
CD28 Blockade Bioassay
CD40 Bioassay
CTLA-4 Blockade Bioassay
FcγRI ADCP Bioassay
FcγRIIa-H ADCP Reporter Bioassay, Complete Kit
FcγRIIa-H ADCP Reporter Bioassay, Core Kits
FcγRIIb CHO-K1 Cells
GITR Bioassay
IL-2 Bioassay
IL-6 Bioassay
IL-12 Bioassay
IL-15 Bioassay
IL-23 Bioassay
LAG-3/MHCII Blockade Bioassay
mFcγRIV ADCC Reporter Bioassay, Complete Kit
mFcγRIV ADCC Reporter Bioassay, Core Kits
OX40 Bioassay
PD-1 + TIGIT Combination Bioassay
PD-1/PD-L1 Blockade Bioassay
PD-L1 Negative Cells
RANKL Bioassay
T Cell Activation Bioassay (IL-2)
T Cell Activation Bioassay (NFAT)
TIGIT/CD155 Blockade Bioassay
TIGIT Negative Cells
VEGF Bioassay

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) discovery, development and monitoring of biologic drugs and vaccines, (3) quality assurance testing of biologic drugs and vaccines, and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the cells or genes stably transfected within the cells. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

General Bioassay Cell-Propagation Model Limited Use Label License
(using Bio-Glo™ Luciferase Assay System)

4-1BB Bioassay, Propagation Model
CD28 Bioassay, Propagation Model
CD28 Blockade Bioassay, Propagation Model
CD40 Bioassay, Propagation Model
CTLA-4 Blockade Bioassay, Propagation Model
FcγRI ADCP Bioassay, Propagation Model
FcγRIIa-H ADCP Bioassay, Propagation Model
FcγRIIb CHO-K1 Cells, Propagation Model
GITR Bioassay, Propagation Model
IL-2 Bioassay, Propagation Model
IL-6 Bioassay, Propagation Model
IL-12 Bioassay, Propagation Model
IL-15 Bioassay, Propagation Model
IL-23 Bioassay, Propagation Model
LAG-3/MHCII Blockade Bioassay, Propagation Model
mFcγRIV ADCC Bioassay, Propagation Model
OX40 Bioassay, Propagation Model
PD-1/PD-L1 Blockade Bioassay, Propagation Model

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) discovery, development and monitoring of biologic drugs and vaccines, (3) quality assurance testing of biologic drugs and vaccines, and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to modify, derivatize, genetically engineer or otherwise create variations of the cells or genes stably transfected within the cells except that recipient may propagate and store the cells for long-term use. In addition, recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

General Bioassay Limited Use Label License
(using Bio-Glo-NL™ Luciferase Assay System)

ADCP Reporter Bioassay (THP-1)
ICOS Bioassay
ICOS Blockade Bioassay
SIRPα/CD47 Blockade Bioassay
SIRPα/CD47 Blockade Bioassay, Fc-Dependent
TIM-3 Bioassay
TLR Bioassay

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use; (2) discovery, development and monitoring of biologic drugs and vaccines; (3) quality assurance testing of biologic drugs and vaccines; and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the cells or genes stably transfected within the cells. In addition, recipient must use Bio-Glo-NL™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

General Bioassay Cell-Propagation Model Limited Use Label License
(using Bio-Glo-NL™ Luciferase Assay System)

ADCP Effector Cells (THP-1), Propagation Model
ADCP Reporter Bioassay Effector Cells (THP-1), Cell Bank
CD47 CHO-K1 Target Cells, Cell Bank
CD47 FcγR-A CHO-K1 Target Cells, Cell Bank
ICOS Bioassay, Propagation Model
ICOS Blockade Bioassay, Propagation Model
SIRPα Effector Cells, Cell Bank
SIRPα/CD47 Blockade Bioassay, Fc-Dependent, Propagation Model
SIRPα/CD47 Blockade Bioassay, Propagation Model
TIM-3 Bioassay, Propagation Model
TLR Bioassay Cells, Cell Bank
TLR Bioassay Cells, Propagation Model

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use; (2) discovery, development and monitoring of biologic drugs and vaccines; (3) quality assurance testing of biologic drugs and vaccines; and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to modify, derivatize, genetically engineer or otherwise create variations of the cells or genes stably transfected within the cells except that recipient may propagate and store the cells for long-term use. In addition, recipient must use Bio-Glo-NL™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

CC1 pan-Kinase Inhibitor Limited Use Label License

CC1 pan-Kinase Inhibitor

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

Cryopreserved Cells, Thaw-and-Use, Limited Use Label License

FcγRIIb aAPC/CHO-K1 Cells
aAPC/CHO-K1 Cells
FcγRIIb CHO-K1 Cells
Membrane RANKL Target Cells
Membrane TNFα Target Cells
Membrane VEGF Target Cells

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use; (2) discovery, development and monitoring of biologic drugs and vaccines; (3) quality assurance testing of biologic drugs and vaccines; and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the cells or genes stably transfected within the cells. In addition, recipient must use luminescent assay reagents purchased from Promega for all luminescence-based assays using this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Cryopreserved Cells, Propagation Model, Limited Use Label License

FcγRIIb aAPC/CHO-K1 Cells, Propagation Model
aAPC/CHO-K1 Cells, Propagation Model
FcγRIIb CHO-K1 Cells, Propagation Model
Membrane RANKL Target Cells, Propagation Model
Membrane TNFα Target Cells, Propagation Model
Membrane VEGF Target Cells, Propagation Model

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use; (2) discovery, development and monitoring of biologic drugs and vaccines; (3) quality assurance testing of biologic drugs and vaccines; and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to modify, derivatize, genetically engineer or otherwise create variations of the cells or genes stably transfected within the cells except that recipient may propagate and store the cells for long-term use. In addition, recipient must use luminescent assay reagents purchased from Promega for all luminescence-based assays using this product, or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

FuGENE® 4K Transfection Reagent Limited Use Label License

FuGENE® 4K Transfection Reagent

FuGENE® 4K is sold with a Limited Use Label License (LULL). You shall use this Product in accordance with all applicable laws, rules and regulations. You may not attempt to reverse engineer this Product. If you are not willing to accept these conditions, the distributor from whom the Product was purchased will accept the return of the unopened Product and provide you with a full refund. However, in the event this Product is opened, you agree to be bound by the conditions of this limited use statement.

FuGENE® 6 Transfection Reagent Limited Use Label License

FuGENE® 6 Transfection Reagent

FuGENE® 6 is sold with a Limited Use Label License (LULL). You shall use this Product in accordance with all applicable laws, rules and regulations. You may not attempt to reverse engineer this Product. If you are not willing to accept these conditions, the distributor from whom the Product was purchased will accept the return of the unopened Product and provide you with a full refund. However, in the event this Product is opened, you agree to be bound by the conditions of this limited use statement.

FuGENE® HD Transfection Reagent Limited Use Label License

FuGENE® HD Transfection Reagent
HaloTag® Complete Pull-Down System

FuGENE® HD is sold with a Limited Use Label License (LULL). You shall use this Product in accordance with all applicable laws, rules and regulations. You may not attempt to reverse engineer this Product. If you are not willing to accept these conditions, the distributor from whom the Product was purchased will accept the return of the unopened Product and provide you with a full refund. However, in the event this Product is opened, you agree to be bound by the conditions of this limited use statement.

FuGENE® SI Transfection Reagent Limited Use Label License

FuGENE® SI Transfection Reagent

FuGENE® SI is sold with a Limited Use Label License (LULL). You shall use this Product in accordance with all applicable laws, rules and regulations. You may not attempt to reverse engineer this Product. If you are not willing to accept these conditions, the distributor from whom the Product was purchased will accept the return of the unopened Product and provide you with a full refund. However, in the event this Product is opened, you agree to be bound by the conditions of this limited use statement.

GloSensor™ cAMP Assay Products Limited Use Label License

GloSensor™ cAMP HEK293 Cell Line
pGloSensor™ cAMP Plasmids

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If the researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide the researcher with a full refund.

Researchers may use this product in their own research solely for the luminescent determination of molecular binding, enzymatic activity or other functional activity. Researchers shall have no right to modify or otherwise create variations of the nucleotide sequence encoding the GloSensor™ technology of this product (i.e., the bioluminescent chimeric protein comprising luciferase and other functional domains). Researchers may transfer derivatives to others provided that recipients agree to be bound by the terms of this label license prior to such transfer. No other use or transfer of this product is authorized without the prior express written consent of Promega. In addition, researchers must either: (1) use GloSensor™ cAMP Reagent for in vitro and in cell applications, and VivoGlo™ Luciferin, In Vivo Grade, for animal applications for all determinations of luminescence activity of this product and derivatives; or (2) contact Promega to obtain a license for use of the product and derivatives in conjunction with luminescent assay reagents not purchased from Promega. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

HaloTag®-HiBiT TCK Bioassay Limited Use Label License
(using Bio-Glo-NB™ Luciferase Assay System)

H929 (HiBiT) TCK Bioassay
Raji (HT-HiBiT) TCK Bioassay
Ramos (HiBiT) TCK Bioassay

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If recipient is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide recipient with a full refund.

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for research use, which includes but is not limited to drug discovery and development, quality assurance testing, and product release assays. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of the product, including but not limited to the nucleotide sequence encoding the HiBiT and HaloTag® peptides for which sequences have been stably transfected within the cells. In addition, recipient must use Bio-Glo-NB™ TCK or Bio-Glo-NB™ Lytic Luciferase Assay Systems purchased from Promega for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega’s. For uses of HaloTag® technology in this product, recipient must either: (1) use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties, or (2) contact Promega to obtain a license if Promega HaloTag® ligands are not to be used.

PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

HaloTag®-HiBiT TCK Bioassay Cell-Propagation Model Limited Use Label License
(using Bio-Glo-NB™ Luciferase Assay System)

H929 (HiBiT) Cell Bank
H929 (HiBiT) TCK Bioassay, Propagation Model
Raji (HT-HiBiT) Cell Bank
Raji (HT-HiBiT) TCK Bioassay, Propagation Model
Ramos (HiBiT) Cell Bank
Ramos (HiBiT) TCK Bioassay, Propagation Model

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If recipient is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide recipient with a full refund.

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for research use, which includes but is not limited to drug discovery and development, quality assurance testing, and product release assays. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient has no right to modify, derivatize, genetically engineer or otherwise create variations of the product, including but not limited to the nucleotide sequence encoding the HiBiT and HaloTag® peptides for which sequences have been stably transfected within the cells. Recipient may propagate and store the cells for long-term use. In addition, recipient must use Bio-Glo-NB™ TCK or Bio-Glo-NB™ Lytic Luciferase Assay Systems purchased from Promega for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega’s. For uses of HaloTag® technology in this product, recipient must either: (1) use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties, or (2) contact Promega to obtain a license if Promega HaloTag® ligands are not to be used.

PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

HaloTag® Ligand Limited Use Label License

HaloCHIP™ Blocking Ligand and System
HaloLink™ Magnetic Beads
HaloLink™ Array Systems
HaloLink™ Resin
HaloTag® Ligands
HaloTag® Protein Purification Resins and Systems
HaloTag® Pull-Down Systems
HaloTag® Standard Protein
Janelia Fluor® HaloTag® Ligands
Magne™ HaloTag® Beads
Protein G HaloTag® Fusion Protein

Researcher may use this product for research use only; no transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. With respect to any uses outside this label license, including any commercial, diagnostic, therapeutic or prophylactic uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

HaloTag® Ligand Building Blocks Limited Use Label License

HaloTag® Iodoacetamide (02) Ligand
HaloTag® Succinimidyl Ester (02) Ligand
HaloTag® Amine (02) Ligand
HaloTag® Amine (04) Ligand
HaloTag® Succinimidyl Ester (04) Ligand
HaloTag® Thiol (04) Ligand
HaloTag® Iodoacetamide (04) Ligand

Researcher may use this product for research use only and may modify or link Promega HaloTag® ligand building blocks to Promega or customer supplied moieties. No transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product or derivatives by a party in exchange for consideration, including, but not limited to, (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. With respect to any uses outside this label license, including any commercial, diagnostic, therapeutic or prophylactic uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

HaloTag® Vector Limited Use Label License

HaloTag® Vectors
HaloTag® Cloning Starter System
HaloTag® Complete Pull-Down System
HaloTag®-CRBN, -PSMD3, -Ubiquitin and -VHL Fusion Vectors
NanoBRET® CRBN and VHL Ternary Complex Starter Kits
NanoBRET® Proteasomal Recruitment and Ubiquitination Starter Kits

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If the researcher is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide the researcher with a full refund.

Researchers may use this product for research use only, no commercial use is allowed. Researchers shall have no right to modify or otherwise create variations of the nucleotide sequence of the HaloTag® gene. Researchers may however clone heterologous DNA sequences at either or both ends of said HaloTag® gene so as to create fused gene sequences provided that the coding sequence of the resulting HaloTag® gene has no more than four (4) deoxynucleotides missing at the affected terminus when compared to the intact HaloTag® gene sequence. In addition, researchers must do one of the following in conjunction with use of the product: (1) use Promega HaloTag® ligands, which can be modified or linked to Promega or customer-supplied moieties, or (2) contact Promega to obtain a license if Promega HaloTag® ligands are not to be used. Researchers may transfer derivatives to others for research use provided that at the time of transfer a copy of this label license is given to the recipients and recipients agree to be bound by the terms of this label license. With respect to any uses outside this label license, including any diagnostic, therapeutic or prophylactic uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THE PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

Anti-HiBiT Antibody Limited Use Label License

Anti-HiBiT Monoclonal Antibody

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

This product and its derivatives may not be further transferred by the researcher and the purchased quantity of the product may be used only by the researcher, and then only for (1) research use, which may include drug discovery and development research; and (2) use in provision of services, that result in transfer of information or data only. No other commercial use of this product or derivatives is allowed. “Commercial use” means any and all uses of this product or derivatives by a party in exchange for money or other consideration, including, but not limited to, (1) use in further product manufacture; and (2) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Researcher may not attempt to reverse engineer this product by any method including, without limitation, any method of sequencing any portion of the product.

With respect to any uses outside this label license, including, without limitation, any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

LgBiT Stable Cell Line Limited Use Label License

HEK293 LgBiT Cell Line

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

Researcher may use this product for research use only, which may include a) drug discovery and development and b) the right to modify, derivatize, genetically engineer or otherwise create variations of the product (“derivatives”). No transfer of this product is allowed; however, researcher may transfer derivatives to others provided that at the time of transfer a copy of this label license is given to recipient and recipient agrees to be bound by the terms of this label license. No commercial use of this product or derivatives is allowed. Commercial use means any and all uses of this product or derivatives by a party in exchange for consideration, including but not limited to (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Researcher shall have no right to modify or otherwise create variations of the nucleotide sequences of the subunits of NanoBiT® Technology.

In addition, researcher must either:
(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product, copies or derivatives thereof; or
(1b) contact Promega to obtain a license for use of the product, copies or derivatives with LARs not manufactured by Promega.

For uses of Nano-Glo®-branded LARs intended for energy transfer (such as bioluminescence resonance energy transfer) to acceptors other than a genetically encoded autofluorescent protein, researcher must:
(2a) use NanoBRET®-branded energy acceptors (e.g., BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this product, copies or derivatives thereof; or
(2b) contact Promega to obtain a license for use of the product, copies or derivatives for energy transfer assays to energy acceptors not manufactured by Promega.

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

Luciferase Limited Use Label License

CheckMate™/Flexi® Mammalian Two-Hybrid Vectors and System
CheckMate™ Mammalian Two-Hybrid Vectors and System
Chroma-Luc™ Vectors
GloResponse™ Luciferase Reporter Cell Lines
pBIND-ERα Vector
pBIND-GR Vector
pCBR and pCBG Basic and Control Vectors
pF9A CMV hRluc-neo Flexi® Vector
pFN11A (BIND) Flexi® Vector
pFN26A (BIND) hRluc-neo Flexi® Vector
pGL4 Luciferase Reporter Vectors
pmirGLO Dual-Luciferase miRNA Target Expression Vector
psiCHECK™ Vectors
pSP-luc+NF Fusion Vector

Researchers may use this product for research use only, no commercial use is allowed. "Commercial use" means any and all uses of this product and derivatives by a party for money or other consideration and may include but is not limited to use in: (1) product manufacture; and (2) to provide a service, information or data; and/or resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Researchers shall have no right to modify or otherwise create variations of the nucleotide sequence of the luciferase gene except that researchers may: (1) create fused gene sequences provided that the coding sequence of the resulting luciferase gene has no more than four deoxynucleotides missing at the affected terminus compared to the intact luciferase gene sequence, and (2) insert and remove nucleic acid sequences in splicing research predicated on the inactivation or reconstitution of the luminescence of the encoded luciferase. No other use or transfer of this product or derivatives is authorized without the prior express written consent of Promega. In addition, researchers must either: (1) use luminescent assay reagents purchased from Promega for all determinations of luminescence activity of this product and its derivatives; or (2) contact Promega to obtain a license for use of the product and its derivatives. Researchers may transfer derivatives to others for research use provided that at the time of transfer a copy of this label license is given to the recipients and recipients agree to be bound by the terms of this label license. With respect to any uses outside this label license, including any diagnostic, therapeutic or prophylactic uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA. This label license relates to Promega patents and/or patent applications on improvements to the luciferase gene.

Lumit® Immunoassay Labeling System Limited Use Label License

Lumit® Immunoassay Labeling Kit

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

Researcher may use this product for research use only and may link Lumit® HaloTag®-LgBiT and/or Lumit® HaloTag®-SmBiT fusion proteins to researcher-supplied moieties. No transfer or commercial use of this product or derivatives is allowed. Commercial use means any and all uses of this product or derivatives by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; and (2) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Notwithstanding the foregoing, researcher may use this product or derivatives in provision of services, information or data to third parties in exchange for consideration, provided that researcher does not transfer the product or derivatives. No other use of this product or its derivatives is authorized without the prior express written consent of Promega.

In addition, researcher must either:
(i) use Lumit®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product and its derivatives; or
(ii) contact Promega to obtain a license for use of the product and its derivatives with LARs not manufactured by Promega.

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

Lumit® NanoLuc® Immunoassay Labeling System Limited Use Label License

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

Researcher may use this product for research use only and may link Lumit® NanoLuc®-HaloTag® fusion proteins to researcher-supplied moieties. No transfer or commercial use of this product or derivatives is allowed. Commercial use means any and all uses of this product or derivatives by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; and (2) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Notwithstanding the foregoing, researcher may use this product or derivatives in provision of services, information or data to third parties in exchange for consideration, provided that researcher does not transfer the product or derivatives. No other use of this product or its derivatives is authorized without the prior express written consent of Promega.

In addition, researcher must either:
(i) use Lumit®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product and its derivatives; or
(ii) contact Promega to obtain a license for use of the product and its derivatives with LARs not manufactured by Promega.

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

Lumit® Secondary Antibody Conjugates Limited Use Label License

Anti-Mouse Ab, LgBiT
Anti-Mouse Ab, SmBiT
Anti-Rabbit Ab, LgBiT
Anti-Rabbit Ab, SmBiT
Anti-Goat Ab, LgBiT
Anti-Goat Ab, SmBiT

NanoBiT® ORF TE Vector Limited Use Label License

LgBiT and SmBiT(q) RAS and RAF Fusion Vectors
NanoBRET® TE Intracellular RAF Dimer Assays
NanoBRET® TE Intracellular RAS Assays

Researchers shall have no right to modify or otherwise create variations of the nucleotide sequences of the subunits of NanoBiT® Technology. No other use of this product or its derivatives is authorized without the prior express written consent of Promega.

In addition, researcher must:

(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product; or

(1b) contact Promega to obtain a license for use of the product with LARs not manufactured by Promega.

For uses of this product for energy transfer (such as bioluminescence resonance energy transfer), researcher must:

(2a) use NanoBRET®-branded luminescent assay reagents (LARs; e.g., NanoBRET® Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine®/Inhibitor for all determinations of luminescent activity; and

(2b) use NanoBRET®-branded energy acceptors (e.g., NanoBRET® tracers, NanoBRET® dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity; or

(2c) contact Promega to obtain a license for use of the product for energy transfer assays using energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.

NanoBiT® Systems Limited Use Label License

LgBiT Expression Vector
NanoBiT® Starter Systems
NanoBiT® PPI Control Pair (FKBP, FRB)
pBiT3.1-N[CMV/HiBiT/Blast] Vector
pBiT3.1-C[CMV/HiBiT/Blast] Vector
pBiT3.1-secN[CMV/HiBiT/Blast] Vector
pFC37K HiBiT CMV-neo Flexi® Vector
pFN38K HiBiT CMV-neo Flexi® Vector
pFN39K secHiBiT CMV-neo Flexi® Vector

No transfer of this product is allowed. Researchers may use this product in their own research and they may transfer derivatives to others for research use provided that at the time of transfer a copy of this label license is given to recipients and recipients agree to be bound by the terms of this label license.

Researchers shall have no right to modify or otherwise create variations of the nucleotide sequences of the subunits of NanoBiT® Technology, except that researchers may create fused gene sequences at the termini of the subunits of NanoBiT® Technology. No other use of this product or its derivatives is authorized without the prior express written consent of Promega.

In addition, researchers must either:
(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product and its derivatives, or
(1b) contact Promega to obtain a license for use of the product and its derivatives with LARs not manufactured by Promega.

For uses of Nano-Glo®-branded LARs intended for energy transfer (such as bioluminescence resonance energy transfer) to acceptors other than a genetically encoded autofluorescent protein, researchers must either:
(2a) use NanoBRET®-branded energy acceptors (e.g., BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this product and its derivatives, or
(2b) contact Promega to obtain a license for use of the product and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega.

Researcher has no right to modify, derivatize, genetically engineer or otherwise create variations of the NanoBiT® Control Vectors, except that researcher may propagate and store NanoBiT® Control Vectors for use in NanoBiT® assays. With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NanoBRET® Dyes Limited Use Label License

NanoBRET® 590 C3 Azide
NanoBRET® 590 C4 SE
NanoBRET® 590 PEG(O4) SE
NanoBRET® 590 SE

Researcher may use this product for research use only, which shall include, without limitations, researcher’s (a) use of the product in its research and development of commercial products (provided that no such product requires the practice of Promega technology) (“Researcher Products”) or (b) use of any data generated using the product for the regulatory approval of such Researcher Products.

Researcher may not modify the product except to link the product to Promega or other non-Promega moieties (“Derivatives”).

For uses of this product and/or Derivatives for energy transfer (such as bioluminescence resonance energy transfer), researcher must:
(1a) use NanoLuc®-branded or NanoBiT®-branded luciferase, subject to any relevant label licenses, for all energy transfer determinations conducted with this product and/or Derivatives; and
(1b) use NanoBRET®-branded luminescent assay reagents (LARs; e.g., NanoBRET® Nano-Glo® Substrate, Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine®/Inhibitor) manufactured by Promega for all determinations of luminescent activity; or
(1c) contact Promega to obtain a license for use of the product or Derivatives with luciferases or LARs not manufactured by Promega.

Except as outlined in (2a) or (2b) below, researcher has no right to i) sell or transfer the product and/or Derivatives to another entity; (ii) sell data or information generated using the product and/or Derivatives to another entity; or iii) sell any product manufactured using the product and/or Derivatives to another entity.
(2a) If researcher is a contract research organization (“CRO”), such CRO may use the product solely on behalf of a single CRO customer to generate Derivatives and transfer or sell such Derivatives or data or information generated using the product and/or Derivatives to the single CRO customer, provided that CRO provides its single customer with a copy of this label license with the transfer of any Derivatives and the CRO customer agrees to comply with this label license for any use of the Derivatives; or
(2b) If researcher is not a CRO, researcher may transfer this product and/or Derivatives to a CRO in order to have CRO generate Derivatives solely on behalf of researcher or have CRO use Derivatives to provide researcher information, data or new Derivatives, and CRO may transfer the information, data or Derivatives to researcher, provided that researcher provides CRO with a copy of this label license and CRO agrees to comply with the terms of this label license.

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic, or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NanoBRET® Interaction Assays Limited Use Label License

NanoBRET® Interaction Assays and PPI Control Vectors and Systems

Researcher may use this product for research use only; no transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product or derivatives by a party in exchange for consideration, including, but not limited to, (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Researcher shall have no right to modify or otherwise create variations of the nucleotide sequence of the luciferase gene or the HaloTag® gene except that researcher may create fused gene sequences provided that the coding sequence of the resulting luciferase gene or HaloTag® gene has no more than four deoxynucleotides missing at the affected terminus compared to the intact gene sequence. No other use of this product or derivatives is authorized without the prior express written consent of Promega.

In addition, researcher must:
(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product and its derivatives; or
(1b) contact Promega to obtain a license for use of the product and its derivatives with LARs not manufactured by Promega.

For uses of Nano-Glo®-branded LARs intended for energy transfer (such as bioluminescence resonance energy transfer) to acceptors other than a genetically encoded autofluorescent protein, researcher must:
(2a) use NanoBRET®-branded energy acceptors (e.g., BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this product and its derivatives; or
(2b) contact Promega to obtain a license for use of the product and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega.

Researcher may transfer derivatives to others for research use provided that at the time of transfer a copy of this label license is given to the recipients and recipients agree to be bound by the terms of this label license. With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NanoBRET® TE Intracellular Tracers Limited Use Label License

NanoBRET® TE Intracellular Kinase Assays and Detection Reagents, K-3, K-4, K-5, K-8, K-9, K-10, K-11, K-12
NanoBRET® TE Tracers, K-3, K-4, K-5, K-8, K-9, K-10, K-11, K-12

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

Researcher may use this product for research use only; no commercial use is allowed. Commercial use means any and all uses of this product by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product, whether or not such product is resold for use in research. Researcher shall have no right to modify or otherwise create variations of the product. No other use or transfer of this product is authorized without the prior express written consent of Promega.

For uses of this product for energy transfer (such as bioluminescence resonance energy transfer), researcher must:
(a) use NanoLuc®-branded luciferase or derivatives for all energy transfer determinations conducted with this product; and
(b) use NanoBRET®-branded luminescent assay reagents (LARs; e.g., NanoBRET® Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine®/Inhibitor for all determinations of luminescent activity; or
(c) contact Promega to obtain a license for use of the product with LARs not listed above or manufactured by Promega.

In addition, researcher must:
Contact Promega to obtain a license for use of the product in assays not involving bioluminescence resonance energy transfer (BRET).

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NanoBRET® TE LAR Limited Use Label License

Intracellular TE Nano-Glo® Substrate/Inhibitor
Intracellular TE Nano-Glo® Vivazine® Substrate/Inhibitor
NanoBRET® TE Intracellular Kinase Assays and Detection Reagents, K-3, K-4, K-5, K-8, K-9, K-10, K-11, K-12
NanoBRET® TE Intracellular RAF Dimer Assays
NanoBRET® TE Intracellular RAS Assays
NanoBRET® TE Intracellular RAS Detection Reagents
NanoBRET® TE K192 Kinase Selectivity System
NanoBRET® TE K192 Kinase Selectivity System with NanoBRET® TE Selectivity DNA Controls
NanoBRET® TE CDK Selectivity Systems A and B

NanoBRET® TE Selectivity Tracers Limited Use Label License

NanoBRET® TE Intracellular RAF Dimer Assays
NanoBRET® TE Intracellular RAS Assays
NanoBRET® TE Intracellular RAS Detection Reagents
NanoBRET® TE CDK Selectivity Systems A and B
NanoBRET® TE K192 Kinase Selectivity System
NanoBRET® TE K192 Kinase Selectivity System with NanoBRET® TE Selectivity DNA Controls

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

Researcher may use this product for research use only; no commercial use is allowed. Commercial use means any and all uses of this product by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product, whether or not such product is resold for use in research. Researcher shall have no right to modify or otherwise create variations of the product. No other use or transfer of this product is authorized without the prior express written consent of Promega.

For uses of this product for energy transfer (such as bioluminescence resonance energy transfer), researcher must:
(a) use NanoLuc®-branded luciferase or derivatives, or subunits of the NanoBiT® technology for all energy transfer determinations conducted with this product; and
(b) use NanoBRET®-branded luminescent assay reagents (LARs; e.g., NanoBRET® Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine®/Inhibitor for all determinations of luminescent activity; or
(c) contact Promega to obtain a license for use of the product with LARs not listed above or manufactured by Promega.

In addition, researcher must:
Contact Promega to obtain a license for use of the product in assays not involving bioluminescence resonance energy transfer (BRET).

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NanoBRET® TE Selectivity Vector Panel Limited Use Label License

NanoBRET® TE K192 Kinase Vector Plates
NanoBRET® TE K192 Kinase Vector Panel
NanoBRET® TE CDK Vector Panels A and B
NanoBRET® TE K192 Kinase Selectivity System
NanoBRET® TE K192 Kinase Selectivity System with NanoBRET® TE Selectivity DNA Controls
NanoBRET® TE CDK Selectivity Systems A and B

BY USE OF THIS PRODUCT, USER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If user is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide user with a full refund.

User may use this product for research use only; however, no amplification or isolation of the vector components of this product and no transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product by a party in exchange for consideration, including, but not limited to: (1) use in further product manufacture; and (2) resale of the product, whether or not such product is resold for use in research. User shall have no right to manufacture or have a third party manufacture the vector components within this product for any purpose. User shall have no right to modify or otherwise create variations of the nucleotide sequence of the luciferase gene. Notwithstanding the foregoing, user may use this product in provision of services to third parties in exchange for consideration; however, user may not transfer the product to third parties. No other use of this product is authorized without the prior express written consent of Promega.

In addition, user must:
(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product; or
(1b) contact Promega to obtain a license for use of the product with LARs not manufactured by Promega.

For uses of this product for energy transfer (such as bioluminescence resonance energy transfer), user must:
(2a) use NanoBRET®-branded energy acceptors (e.g., NanoBRET® tracers, NanoBRET® dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity; and
(2b) use NanoBRET®-branded LARs (e.g., NanoBRET® Nano-Glo® Substrate) or Intracellular TE Nano-Glo® Substrate/Inhibitor or Intracellular TE Nano-Glo® Vivazine®/Inhibitor for all determinations of luminescent activity; or
(2c) contact Promega to obtain a license for use of the product for energy transfer assays using energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

Nano-Glo® Fluorofurimazine in vivo Substrate Limited Used Label License

Nano-Glo® Fluorofurimazine in vivo Substrate (FFz)

Researchers may use this product for research use only, limited to animal imaging experiments or experiments performed to prepare for such animal imaging experiments; no commercial use is allowed. “Commercial use” means any and all uses of this product by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; and (2) resale of the product, whether or not such product is resold for use in research. Researchers shall have no right to modify or otherwise create variations of the product. No other use or transfer of this product is authorized without the prior express written consent of Promega. Notwithstanding the foregoing, researcher may use this product in provision of services, information or data to third parties in exchange for consideration, provided that researcher does not transfer the product.

For uses of Nano-Glo®-branded reagents intended for energy transfer (such as bioluminescence resonance energy transfer) to acceptors other than a genetically encoded autofluorescent protein, researchers must:
(a) use NanoBRET®-branded energy acceptors (e.g., BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this product; or
(b) contact Promega to obtain a license for use of the product for energy transfer assays to energy acceptors not manufactured by Promega.

Nano-Glo® Luciferase Assay System Limited Use Label License

Nano-Glo® Luciferase Assay System
Nano-Glo® Dual-Luciferase® Reporter Assay System
Nano-Glo® Dual-Luciferase® Reporter Assay/Vector Bundles
Nano-Glo® Live Cell Assay System
NanoBRET® Nano-Glo® Detection System and Substrate
NanoBRET® Nano-Glo® Kinetic Detection System
NanoBRET® Starter Systems
NanoBRET® Interaction Assays
Nano-Glo® HiBiT Blotting System
Nano-Glo® HiBiT Extracellular Detection System
Nano-Glo® HiBiT Lytic Detection System
Nano-Glo® Endurazine Live Cell Substrate
Nano-Glo® Vivazine® Live Cell Substrate
Nano-Glo® Extended Live Cell Substrates (Trial Pack)
NanoBRET® CRBN and VHL Ternary Complex Starter Kits
NanoBRET® Proteasomal Recruitment and Ubiquitination Starter Kits

Researchers may use this product for research use only; no commercial use is allowed. Commercial use means any and all uses of this product by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product, whether or not such product is resold for use in research. Researchers shall have no right to modify or otherwise create variations of the product. No other use or transfer of this product is authorized without the prior express written consent of Promega.

NanoLuc® and NanoBiT® Reporter mRNAs Limited Use Label License

ViaScript™ LgBiT mRNA Delivery Systems

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

Researcher may use this product for research use only; no transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; and (2) resale of the product, whether or not such product is resold for use in research. Notwithstanding the foregoing, researcher may use this product in provision of services, information or data to third parties in exchange for consideration, provided that researcher does not transfer the product. Researcher has no right to reverse engineer this product.

In addition, researcher must either:
(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product and its derivatives; or
(1b) contact Promega to obtain a license for use of the product and its derivatives with LARs not manufactured by Promega.

For uses of Nano-Glo®-branded LARs intended for energy transfer (such as bioluminescence resonance energy transfer) to acceptors other than a genetically encoded autofluorescent protein, researcher must either:
(2a) use NanoBRET®-branded energy acceptors (e.g., BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this product and its derivatives; or
(2b) contact Promega to obtain a license for use of the product and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega.

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

NanoLuc® Coincidence Vector Limited Use Label License

NanoLuc® Coincidence Vectors

Researcher may use this product for research use only; no transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product or derivatives by a party in exchange for consideration, including, but not limited to, (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Researcher shall have no right to modify or otherwise create variations of the nucleotide sequences of the luciferase genes except that researcher may (1) create fused gene sequences provided that the coding sequences of the resulting luciferase genes have no more than four deoxynucleotides missing at the affected terminus compared to the intact luciferase gene sequences; and (2) insert and remove nucleic acid sequences in splicing research predicated on the inactivation or reconstitution of the luminescence of the encoded luciferases. No other use of this product or derivatives is authorized without the prior express written consent of Promega.

For uses of Nano-Glo®-branded LARs intended for energy transfer (such as bioluminescence resonance energy transfer) to acceptors other than a genetically encoded autofluorescent protein, researcher must:
(2a) use NanoBRET®-branded energy acceptors (e.g., BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this product and its derivatives; or
(2b) contact Promega to obtain a license for use of the product and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega.

NanoLuc® Labeling System Limited Use Label License

NanoLuc® Labeling System

Researcher may use this product for research use only and may link NanoLuc®-HaloTag® fusion proteins to researcher-supplied moieties. No transfer or commercial use of this product or derivatives is allowed. Commercial use means any and all uses of this product or derivatives by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; and (2) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Notwithstanding the foregoing, researcher may use this product or derivatives in provision of services, information or data to third parties in exchange for consideration, provided that researcher does not transfer the product or derivatives. No other use of this product or its derivatives is authorized without the prior express written consent of Promega.

In addition, researcher must either:
(i) use Lumit®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product and its derivatives; or
(ii) contact Promega to obtain a license for use of the product and its derivatives with LARs not manufactured by Promega.

NanoLuc® Luciferase Limited Use Label License

NanoLuc® Vectors
Nano-Glo® Dual-Luciferase® Reporter Assay/Vector Bundles
NanoBRET® Starter Systems
NanoBRET® CRBN and VHL Ternary Complex Starter Kits
NanoBRET® Proteasomal Recruitment and Ubiquitination Starter Kits
NanoBRET® TE K192 Kinase Selectivity System with NanoBRET® TE Selectivity DNA Controls
NanoBRET® TE Selectivity DNA Controls

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

Researchers may use this product for research use only; no transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product or derivatives by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product or its derivatives, whether or not such product or derivatives are resold for use in research. Researchers shall have no right to modify or otherwise create variations of the nucleotide sequence of the luciferase gene except that researcher may (1) create fused gene sequences provided that the coding sequence of the resulting luciferase gene has no more than four deoxynucleotides missing at the affected terminus compared to the intact luciferase gene sequence; and (2) insert and remove nucleic acid sequences in splicing research predicated on the inactivation or reconstitution of the luminescence of the encoded luciferase. No other use of this product or derivatives is authorized without the prior express written consent of Promega.

In addition, researchers must:
(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product and its derivatives; or
(1b) contact Promega to obtain a license for use of the product and its derivatives with LARs not manufactured by Promega.

For uses of Nano-Glo®-branded LARs intended for energy transfer (such as bioluminescence resonance energy transfer) to acceptors other than a genetically encoded autofluorescent protein, researchers must:
(2a) use NanoBRET®-branded energy acceptors (e.g., BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity by this product and its derivatives; or
(2b) contact Promega to obtain a license for use of the product and its derivatives for energy transfer assays to energy acceptors not manufactured by Promega.

Researchers may transfer derivatives to others for research use provided that at the time of transfer a copy of this label license is given to the recipients and recipients agree to be bound by the terms of this label license. With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

NanoLuc® ORF Vector Limited Use Label License

NanoBRET® TE Intracellular BET BRD Assay
NanoBRET® TE BET BRD DNA Bundle
NanoBRET® TE Intracellular HDAC Assay
NanoBRET® TE HDAC DNA Bundle
NanoBRET® TE Intracellular HDAC Complete Kit
NanoBRET® TE Intracellular BET BRD Complete Kit
NanoBRET® TE Intracellular Kinase Assays, K-5 and K-4
NanoBRET® TE Intracellular Kinase Detection Reagents, K-5 and K-4

In addition, researcher must:
(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product; or
(1b) contact Promega to obtain a license for use of the product with LARs not manufactured by Promega.

For uses of this product (Nano-Glo® ORF Vector) for energy transfer (such as bioluminescence resonance energy transfer), researcher must:
(2a) use NanoBRET®-branded luminescent assay reagents (LARs; e.g., NanoBRET® Nano-Glo® Substrate) or Intracellular TE Nano-Glo® Substrate/Inhibitor for all determinations of luminescent activity; and
(2b) use NanoBRET®-branded energy acceptors (e.g., NanoBRET® tracers, NanoBRET® dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity; or
(2c) contact Promega to obtain a license for use of the product for energy transfer assays using energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.

NanoLuc® ORF TE Vector Limited Use Label License

NanoBRET® TE Intracellular Kinase Assays, K-3, K-4, K-5, K-8, K-9, K-10, K-11, K-12
NanoLuc® Kinase Fusion Vectors
NanoLuc®-BRD4 FL Fusion Vector
NanoBRET® TE Intracellular BET BRD Assay
NanoBRET® TE BET BRD DNA Bundle
NanoBRET® TE Intracellular HDAC Assay
NanoBRET® TE HDAC DNA Bundle
NanoBRET® TE Intracellular E3 Ligase Assays, CRBN, VHL
NanoLuc® E3 Ligase Fusion Vectors
NanoBRET® TE CDK Selectivity Systems A and B
NanoBRET® TE K192 Kinase Selectivity System with NanoBRET® TE Selectivity DNA Controls
NanoBRET® TE Selectivity DNA Controls

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.

Researcher may use this product for research use only; no transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product, whether or not such product is resold for use in research. Researcher shall have no right to modify or otherwise create variations of the nucleotide sequence of the luciferase gene. No other use of this product is authorized without the prior express written consent of Promega.

In addition, researcher must:
(1a) use Nano-Glo®-branded luminescent assay reagents (LARs) for all determinations of luminescence activity of this product; or
(1b) contact Promega to obtain a license for use of the product with LARs not manufactured by Promega.

For uses of this product (NanoLuc® ORF Vector) for energy transfer (such as bioluminescence resonance energy transfer), researcher must:
(2a) use NanoBRET®-branded luminescent assay reagents (LARs; e.g., NanoBRET® Nano-Glo® Substrate), Intracellular TE Nano-Glo® Substrate/Inhibitor, or Intracellular TE Nano-Glo® Vivazine®/Inhibitor for all determinations of luminescent activity; and
(2b) use NanoBRET®-branded energy acceptors (e.g., NanoBRET® tracers, NanoBRET® dyes, BRET-optimized HaloTag® ligands) for all determinations of energy transfer activity; or
(2c) contact Promega to obtain a license for use of the product for energy transfer assays using energy acceptors not manufactured by Promega. No license is needed if the energy transfer acceptor is a genetically encoded autofluorescent protein.

With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

T Cell Activation Bioassay (NFAT) and (IL-2) CPM Limited Use Label License

T Cell Activation Bioassay (NFAT), Propagation Model
T Cell Activation Bioassay (IL-2), Propagation Model

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use, (2) discovery, development and monitoring of biologic drugs and vaccines, (3) quality assurance testing of biologic drugs and vaccines, and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. "Commercial use" means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient may genetically engineer the cell line using exogenous nucleic acid sequences provided by Researcher. In addition, recipient may propagate and store the cells for long-term use. Recipient must use Bio-Glo™ Luciferase Assay System purchased from Promega Corporation for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega's. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

T Cell Activation Bioassay (TCRαβ-KO) Cell Bank and CPM Limited Use Label License

T Cell Activation Bioassay (TCRαβ-KO, CD4+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD8+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD4+, CD8+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD8+), Propagation Model
T Cell Activation Bioassay (TCRαβ-KO, CD4+), Propagation Model
T Cell Activation Bioassay (TCRαβ-KO, CD4+, CD8+), Propagation Model

This product may not be further sold or transferred by the recipient and may be used only by the recipient, and then only for (1) research use; (2) discovery, development and monitoring of biologic drugs and vaccines; (3) quality assurance testing of biologic drugs and vaccines; and (4) product release assays for biologic drugs and vaccines. No other commercial use is allowed. “Commercial use” means any and all uses of this product by recipient for monetary or other consideration, including providing a service, information or data to unaffiliated third parties, and resale of this product for any use. Recipient may genetically engineer the cell line using exogenous nucleic acid sequences provided by recipient. Recipient may propagate and store the cells for long-term use. In addition, recipient must use Bio-Glo-NL™ Luciferase Assay System purchased from Promega for all luminescence assays using this product or contact Promega to obtain a license for use of this product with reagents other than Promega’s. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARD TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

T Cell Activation Bioassay (TCRαβ-KO) Cell Bank and CPM Limited Use Label License from Broad

T Cell Activation Bioassay (TCRαβ-KO, CD4+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD8+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD4+, CD8+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD8+), Propagation Model
T Cell Activation Bioassay (TCRαβ-KO, CD4+), Propagation Model
T Cell Activation Bioassay (TCRαβ-KO, CD4+, CD8+), Propagation Model

By purchase of this material, Promega Corporation (“Promega”) conveys to purchaser (the “Limited Licensee”) the non-transferable right to use the material purchased from Promega and derivatives made by Limited Licensee solely for research conducted by Limited Licensee in accordance with the following requirements: (i) Limited Licensee shall not sell or otherwise transfer material or derivatives to any other person or entity, or use material or derivatives to perform services for the benefit of any other person or entity, except to transfer the material or derivatives to a Limited Licensee affiliate provided such affiliate agrees to be bound by the terms of this Limited License; (ii) Limited Licensee shall use material and derivatives only for its internal research within the Customer Field, which may include internal research within the Customer Field in connection with product research, and not for any Commercial Purposes; (iii) Limited Licensee shall use material and derivatives in compliance with all applicable laws and regulations, including without limitation applicable human health and animal welfare laws and regulations; (iv) Institutions shall provide no warranties of any kind to Limited Licensee (statutory or implied) concerning the Intellectual Property or material or derivatives, including without limitation, as to product quality, condition, description, merchantability, fitness for a particular purpose, noninfringement of intellectual property rights or the absence of latent or other defects, and all such warranties are hereby expressly disclaimed; (v) Institutions shall expressly disclaim any warranty regarding results obtained through the use of material or derivatives, including without limitation any claim of inaccurate, invalid or incomplete results; (vi) Institutions and their directors, trustees, officers, employees, agents, faculty, affiliated investigators and students shall have no liability to Limited Licensee, including without limitation, for any loss of use or profits, business interruption or any consequential, incidental, special or other indirect damages of any kind, regardless of how caused and regardless of whether an action in contract, tort, strict product liability or otherwise; (vii) Limited Licensee shall indemnify, defend and hold harmless the Indemnitees and HHMI Indemnitees against any liability, damage, loss or expense (including without limitation reasonable attorneys’ fees and expenses) incurred by or imposed upon any of the Indemnitees or HHMI Indemnitees, as applicable, in connection with any claims, suits, investigations, actions, demands or judgments arising out of or related to the exercise of any rights granted to Limited Licensee under this limited license or any breach of limited license by such Limited Licensee, provided that, to the extent the foregoing is not permitted by law, Limited Licensee agrees, to the extent permitted by law, that it, and not the Indemnitees or HHMI Indemnitees, as applicable, shall be responsible for any liability, damage, loss or expense arising out of or related to the exercise of any rights granted to Limited Licensee under this limited license or any breach of this limited license by Limited Licensee; and (viii) material and derivatives and their use may be the subject of one or more issued patents or pending patent applications owned by one or more Institutions, and the purchase of material does not convey a license under any claims in the foregoing patents or patent applications directed to the material or derivatives or use, production or commercialization thereof, except as expressly set forth in this limited license. Nothing in this limited license shall be construed to confer any rights upon Limited Licensee by implication, estoppel or otherwise as to any technology or patent rights of Broad or any other entity other than the Intellectual Property. In addition, nothing in this limited license shall be construed to confer upon Limited Licensee or any third party any rights under or to the Intellectual Property outside of the Customer Field.

Commercial Purposes means (a) the practice, performance or provision of any methods, process or service; or (b) the manufacture, production, sale, use, distribution, disposition or importing of any product, in each case (a) or (b) for consideration of any kind, for the purpose of sale or commercial exploitation, or on any other commercial basis.

Customer Field means use as a research tool for research purposes and use for quality control/quality assurance testing and product lot release assays, provided, however, that notwithstanding the foregoing, the Customer Field shall expressly exclude:

Any human or clinical use, including, without limitation, any administration into humans or any diagnostic or prognostic use;
Any human germline modification, including modifying the DNA of human embryos or human reproductive cells;
Any in vivo veterinary or livestock use;
The development, manufacture (including any bioproduction), distribution, importation, exportation, transportation, sale, offer for sale, marketing, promotion or other exploitation or use of the Intellectual Property or the material or derivatives as a therapeutic or diagnostic for humans or animals;
Products that provide nutritional benefits and are regulated by a regulatory authority as a drug or biologic pursuant to Section 505 of the Federal Food, Drug, and Cosmetic Act of 1938, as amended, Section 351 of the Public Health Service Act of 1944, as amended, or any successor laws, or equivalent laws or regulations in jurisdiction outside the United States;
Any agricultural use, including but not limited to, the use or application in the cultivation, growth, manufacture, exportation, or production of any tobacco product; and
Any use or application relating to gene drive.

HHMI Indemnitees means Howard Hughes Medical Institute and its trustees, officers, employees and agents.

Indemnitees means each Institution, their affiliates, and their current and former trustees, directors, officers, faculty, affiliated investigators, students, employees, medical and professional staff and agents and their respective successors, heirs and assigns.

Institutions means each of The Broad Institute, Inc., Massachusetts Institute of Technology, Harvard College, University of Iowa Research Foundation, University of Tokyo, The Rockefeller University, New York University, New York Genome Center, and Whitehead Institute of Biomedical Research collectively.

Intellectual Property means (a) any patents and patent applications listed on Appendix A; (b) any substitutions, divisions, continuations, reissues, renewals, re-examinations or extensions of any patents or patent applications of (a), any continuations-in-part of any patents or patent applications of (a) to the extent the claims are directed to subject matter specifically described in a patent or patent application set forth on Appendix A, and any application claiming priority to a provisional application set forth on Appendix A to the extent the claims are directed to subject matter specifically described in a provisional patent application set forth on Appendix A; (c) any letters patents and/or the equivalent issuing therefrom in any jurisdiction based on, and only to the extent of, any of the foregoing; and (d) any foreign or international equivalents of any of the foregoing, including without limitation any applications filed under the Patent Cooperation Treaty.

Appendix A, Broad IP List

BROADTECHID	APPLICANTS	EXEMPLARYFAMILYSERIALNO
BI-2011/008	Broad,MIT,HarvardandRockefeller	PCT/US2013/074611; WO2014093595
BI-2011/008B	Broad,MITandHarvard	14/259,420
BI-2011/008A	BroadandMIT	PCT/US2013/074743; WO2014093661
BI-2011/008C	Broad, MIT, and Harvard	PCT/US2013/074790; WO2014093694
BI-2011/020	Broad,MITandHarvard	PCT/US2013/051418; WO2014018423
BI-2012/084A	BroadandMIT	PCT/US2013/074825; WO2014093718
BI-2012/084B	Broad,MITandHarvard	PCT/US2013/074812; WO2014093709
BI-2013/003	Broad,MITandHarvard	PCT/US2013/074667; WO2014093622
BI-2013/003D	Broad,MITandHarvard	PCT/US2014/041803; WO2014201425
BI-2013/004E	Broad,MITandHarvard	PCT/US2013/074691; WO2014093635
BI-2013/004F	Broad,MITandHarvard	PCT/US2013/074736; Wo2014093655
BI-2013/004G	Broad,MITandHarvard	PCT/US2013/074819; WO2014093712
BI-2013/007	Broad,MITandHarvard	14/855,046; US20160068822
BI-2013/066	Broad,MITandHarvard	PCT/US2014/041800; WO2014204724
BI-2013/073	BroadandMIT	PCT/US2014/041806; WO2014204727
BI-2013/085	Broad,MITandWhitehead	15/141,348; US20160251648
BI-2013/087J	Broad,Editas*,IowaandMIT	PCT/US2014/064663; WO2015070083
BI-2013/087M	Broad,IowaandMIT	PCT/US2014/069902; WO2015089354
BI-2013/087V	Broad,IowaandMIT	PCT/US2014/069897; WO2015089351
BI-2013/093	Broad,MITandTokyo	15/171,141; US20160340660
BI-2013/094	Broad,MITandRockefeller	PCT/US2014/070135; Wo2015089465
BI-2013/098	BroadandMIT	PCT/US2014/070068; WO2015089427
BI-2013/099	Broad,MITandHarvard	PCT/US2014/041804; WO2014204726
BI-2013/101	BroadandMIT	PCT/US2014/070127; WO2015089462
BI-2013/103	BroadandMIT	PCT/US2014/041808; WO201404728
BI-2013/105	Broad,MITandHarvard	PCT/US2014/041809; WO2014204729
BI-2013/107	BroadandMIT	PCT/US2014/070057; WO2015089419
BI-2013/112	BroadandMIT	PCT/US2013/074800; WO2014093701
BI-2013/113	Broad,MITandHarvard	PCT/US2014/070152; WO2015089473
BI-2014/005	Broad,MIT,HarvardandTokyo	PCT/US2014/070175; WO2015089486
BI-2014/061	Broad,MITandHarvard	PCT/US2015/045504; WO2016028682
BI-2014/069	BroadandMIT	15/467,888; US20180010134
BI-2014/071	BroadandMIT	15/349,603; US20170107536
BI-2014/072	BroadandMIT	15/467,949; US20180044662
BI-2014/084	Broad,MITandHarvard	15/469,081; US20180057810
BI-2014/097	Broad,MITandHarvard	PCT/US2015/067177; WO2016106244
BI-2014/100	Broad,MITandHarvard	PCT/US2015/065385; WO2016094867
BI-2014/101	Broad,MITandHarvard	15/632,067; US20170306335
BI-2014/103	BroadandMIT	PCT/US2015/067138; WO2016100974
BI-2014/106	BroadandMIT	PCT/US2015/065393; WO2016094872
BI-2014/107	BroadandMIT	15/619,735; US20170349894
BI-2014/108	BroadandMIT	15/619,737; US20170349914
BI-2014/113	BroadandMIT	15/640,103; US20180112255
BI-2015/002	Broad,MIT,HarvardandTokyo	PCT/US2016/038252; WO2016205759
BI-2015/052	BroadandMIT	PCT/US2016/038034; WO2016205613
BI-2015/053	MIT	PCT/US2016/038205; WO2016205728
10086	BroadandMIT	PCT/US2017/047458; WO2018035387
10114	BroadandMIT	PCT/US2017/053795; WO2018064208
10125	BroadandMIT	62/502,064 62/564,102
10209	Broad,Harvard,MIT,NewYorkUniversity and NYGenomeCenter	62/529,573

*Broad does not purport to grant any rights in the asterisked applicant's interest in these applications in this Agreement.

T Cell Activation Bioassay (TCRαβ-KO) Cell Bank and CPM Limited Use Label License from Caribou

T Cell Activation Bioassay (TCRαβ-KO, CD4+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD8+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD4+, CD8+), Cell Bank
T Cell Activation Bioassay (TCRαβ-KO, CD8+), Propagation Model
T Cell Activation Bioassay (TCRαβ-KO, CD4+), Propagation Model
T Cell Activation Bioassay (TCRαβ-KO, CD4+, CD8+), Propagation Model

BEFORE OPENING OR USING THIS PRODUCT, PLEASE READ THE TERMS AND CONDITIONS SET FORTH IN THIS LIMITED USE LABEL LICENSE. YOUR USE OF THIS PRODUCT SHALL CONSTITUTE ACKNOWLEDGMENT AND ACCEPTANCE OF THESE TERMS AND CONDITIONS. If you do not agree to use this Product pursuant to the terms and conditions set out in this Limited Use Label License, please contact Promega Corporation within ten (10) calendar days of receipt to return the unused and unopened Product for a full refund; provided, however, that custom-made Products may not be returned for a refund.

Promega is selling this Product under a research use only license from Caribou Biosciences, Inc., under certain patents and patent applications owned or controlled by Caribou. For information on obtaining rights beyond those set forth in this Limited Use Label License please contact licensing@promega.com or Promega Corporation, 2800 Woods Hollow Road, Madison, WI 53711 USA, Attn: Licensing.

The purchase of this Product conveys to you, the Buyer, the NON-TRANSFERABLE right to use this Product solely for Research Use, subject to the conditions set out in this Limited Use Label License. If you wish to use this Product for any purpose other than Research Use, you must first obtain an appropriate license. This Product may not be used for any purpose other than Research Use. Your right to use this Product for Research Use is subject to the following conditions and restrictions:

Research Use means any use for internal research purposes, (e.g., for screening, characterization, quality control/quality assurance testing, product lot release assays, and/or toxicology purposes) for the sole benefit of you, the Buyer.
Research Use specifically excludes the following:
- Sale or otherwise transfer of this Product, including without limitation any material that contains this Product in whole or part or any progeny, modification or derivative of this Product (collectively, “Related Materials”) to any other third party; and
- Commercial purposes and prohibited activities including use of this Product and Related Materials in (i) any sale, marketing, distribution, disposition, importation or exportation, whether for a fee or any other commercial basis; (ii) any commercial activity including, but not limited to, any use in manufacturing or bioproduction; (iii) preclinical or clinical testing or other activity directed toward the submission of data to the U.S. Food and Drug Administration, or any other regulatory agency in any country or jurisdiction where the active agent in such studies comprises this Product; (iv) use in a product for, or for any use in, human or animal therapeutics, diagnostics, or prophylactics; (v) activity in an agricultural field trial or any activity directed toward the submission of data to the U.S. Department of Agriculture or any other agriculture regulatory agency; (vi) modification of the human germline, including editing human embryos or reproductive cells; (vii) stimulation of biased inheritance of a particular gene or trait or set of genes or traits; and/or (viii) use of self-administration.
You, the Buyer, shall use this Product and Related Materials in compliance with all applicable laws and regulations.
No warranties of any kind are provided to the you, the Buyer (statutory or implied), concerning this Product or Related Materials, including without limitation, as to product quality, condition, description, merchantability, fitness for a particular purpose, noninfringement of intellectual property rights, or the absence of latent or other defects, and all such warranties are hereby expressly disclaimed.
Your right to use this Product and Related Materials will terminate immediately if you fail to comply with these terms and conditions.

TransfectNow™ HEK293 Cells Limited Use Label License

TransfectNow™ HEK293 Cells

NOT FOR MEDICAL DIAGNOSTIC USE. FOR IN VITRO USE ONLY. BY USE OF THIS PRODUCT, RECIPIENT AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE STATEMENT. If recipient is not willing to accept the conditions of this limited use statement, and the product is unused, Promega will accept return of the unused product and provide recipient with a full refund.

This product and its transfected derivatives may not be further sold or transferred by recipient and may be used only by recipient, and then only for research use, which includes, but is not limited to, drug discovery and development. No commercial use is allowed. “Commercial use” means any and all uses of this product or its transfected derivatives by recipient for monetary or other consideration, including without limitation (1) product manufacturing, and (2) resale of this product or transfected derivatives for any use. Recipient has no right to propagate, modify, derivatize, genetically engineer or otherwise create variations of this product, except that recipient may transiently transfect these cells for use in generating research data. Notwithstanding the foregoing, recipient may use this product or transfected derivatives in provision of services to third parties in exchange for consideration (“Service Providers”); however, Service Providers may not transfer the product or transfected derivatives to third parties. Notwithstanding the transfer prohibitions of this limited use statement, end-user recipients, including, but not limited to non-profit recipients, and biotech and biopharma recipients, may transfer this product to third-party Service Providers, provided that Service Providers (1) receive a copy of this limited use statement and agree to comply with its terms; (2) use this product only on behalf of end-user recipient; (3) comply with the AdVec, Inc., license requirements described below; and (4) agree not to transfer this product or transfected derivatives to any other party.

Any use of this product by recipients who are for-profit entities (including without limitation biotechnology companies, biopharmaceutical companies and Service Providers) requires a license to HEK293 cell line from AdVec. Academic and other non-profit entities do not require any further license from AdVec. Unlicensed for-profit entities may contact AdVec, Dr. Frank Graham, CEO, at graham@mcmaster.ca.

No other use of this product is authorized without the prior express written consent of Promega. With respect to any uses outside this limited use statement, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING AS TO MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THIS PRODUCT. The terms of this agreement shall be governed under the laws of the State of Wisconsin, USA.

ViaFect™ Transfection Reagent Limited Use Label License

ViaFect™ Transfection Reagent

ViaFect™ Transfection Reagent is sold with a Limited Use Label License.

Researchers may use this product for research use only and in accordance with all applicable laws, rules and regulations. Researchers shall have no right to reverse engineer this product. With respect to any uses outside this label license, including any diagnostic, therapeutic or prophylactic uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE WITH REGARDS TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

PROMEGA LEGAL

Legal and Trademarks

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