Maxwell® DE System

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Automated, Medium- and High-Throughput Separation of Sperm and Non-Sperm Fractions of Sexual Assault Samples

  • Automated washes reduce manual labor and errors in differential extraction
  • Process 1–16 or 1–48 samples in 90 minutes
  • Recover sperm DNA with high efficiency
  • No further purification of sperm and non-sperm lysates required for downstream use with PowerQuant® and PowerPlex® Systems

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Catalog number selected: AS1870

$ 1,600.00
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Maxwell® DE System
48 preps
$ 1,600.00
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Automate Your Differential Extraction Workflow

Forensic labs require efficiency and precision, especially when handling complex samples from sexual assault cases. Manual methods for differential extraction are time-consuming, and their performance can vary depending on the individual analyst.

The Maxwell® DE System enables medium- and high-throughput separation of sperm DNA from casework samples with mixed cell types and eliminates the need for purification when quantification and STR-analysis are performed with PowerQuant® and PowerPlex® Systems. Automation provides consistent and reproducible results for forensic casework analysts who need to efficiently process sexual assault samples to reduce their lab’s SAEK backlog.

Illustration of Maxwell® DE System workflow.
ForensicGrade

Promega forensic products are manufactured in alignment with the ISO 18385 standard. This standard ensures minimal risk of human DNA contamination for products used to collect, store and analyze biological materials for forensic purposes. Learn more.

Shorten Your SAEK Turnaround Time

Many forensic labs face narrow turnaround times for processing sexual assault evidence kit samples. The Maxwell® DE System saves time and labor costs by automating the most difficult steps of differential extraction.

Save Resources with Direct Compatibility

Streamline procurement and inventory management for your lab. As part of a complete SAEK sample workflow, the Maxwell® DE System is optimized for use with PowerQuant® and PowerPlex® Systems and eliminates the need to purify DNA after separating sperm and epithelial cells.

The Maxwell® DE System also includes all components necessary for differential extraction.


Profiles from Fractions Obtained with the Maxwell® DE System

Profile obtained from the epithelial fraction of a post-coital sample obtained using the Maxwell® DE System.
Profile obtained from the sperm fraction of a post-coital sample obtained using the Maxwell® DE System.

Profiles obtained from the epithelial (left) and sperm (right) fractions of the same post-coital sample. Fractions were obtained using the Maxwell® DE System and amplified using the PowerPlex® 35GY System. The concentration of autosomal DNA detected in the epithelial fraction with the PowerQuant® System was 15.3ng/µl. The [Auto]/[Deg] ratio for the epithelial fraction was 3.9. The concentration of autosomal DNA detected in the sperm fraction with the PowerQuant® System was 0.08ng/µl. The [Auto]/[Y] ratio for the sperm fraction was 1.1, and the [Auto]/[Deg] ratio was 2.6.

Maxwell® Instruments Make Forensic Labs More Efficient

Automated DNA extraction saves laboratories time and labor costs and frees staff to work on casework analysis. Capable of processing up to 16 or 48 samples per run, Maxwell® Instruments and Kits meet the varying throughput demands of forensic laboratories.

Explore the Maxwell® FSC Instrument for forensic labs.

Explore the Maxwell® RSC 48 Instrument for higher sample throughput.

DNA Extraction on Maxwell RSC and FSC Instruments

Specifications

What's in the box?

Item Part # Size Available Separately

1-Thioglycerol

A208B-C 1 × 900μl

Proteinase K (PK) Solution

MC500C 2 × 1ml View Product

Maxwell® DE Resuspension Buffer

A837A 1 × 60ml

Nuclease-Free Water

P119H 1 × 25ml View Product

Maxwell® DE Lysis Buffer

A836A 1 × 30ml

Maxwell® DE Elution Buffer

A838A 1 × 20ml

Maxwell® DE Cartridges

AS190A 48 × 1 each

Maxwell® RSC Plunger Pack

AS711A 1 × 48/pack

DNA IQ™ Spin Baskets

V122A 1 × 50/pack View Product

Click-Fit Microtube, 1.5ml

V474A 1 × 100/pack View Product

Elution Tubes, 0.5ml

AS720A 1 × 50/pack View Product

Certificate of Analysis

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Use Restrictions

Not For Medical Diagnostic Use.

Storage Conditions

DD

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Uwe

Uwe

Germany