Maxwell® RSC Instrument
Automated DNA or RNA Extraction with Integrated Quantification
- High-quality nucleic acid purification with minimal steps and less hands-on time
- Integrated Quantus™ Fluorometer for sample quantification
- Intuitive software and touch screen interface
Catalog Number:
Size
Catalog Number: AS4500
Extract High-Quality Nucleic Acids with Less Hands-On Time
The Maxwell® RSC Instrument is a compact, automated nucleic acid purification platform that processes up to 16 samples simultaneously. Using prefilled cartridges and preprogrammed methods, the Maxwell® RSC offers consistent, reliable DNA or RNA extraction in 25–60 minutes, depending upon sample type. The intuitive graphical interface makes the instrument easy to use, and the integrated Quantus™ Fluorometer lets you collect purification and quantification data in one report.
Francis Crick Institute Case Study:
Benchtop Automated Nucleic Acid Purification
It saves me in total about 40 minutes per 12 samples, and I do 4 runs per day, so that is almost half a day.
Yan Tsou, Laboratory Research Scientist
Anthony Nolan Research Institute Case Study:
Long-Read Next-Generation Sequencing Workflow
It really is the workhorse of our lab in terms of DNA extraction… allowing us to process multiple samples at once with minimal hands-on time.
Thomas Turner, Senior Post Doctoral Research Scientist
No Drips, Plugs or Sample Loss with a Paramagnetic Particle Mover
The Maxwell® RSC DNA or RNA extraction methods start with cartridges prefilled with purification reagents and paramagnetic particles, ready for your samples. After sample addition, the Maxwell® RSC moves the paramagnetic particles and associated nucleic acids through multiple steps ultimately yielding highly pure RNA or DNA in 30–100µl.
Because the Maxwell® RSC is a magnetic particle mover, not a liquid handler, it offers advantages over other automated systems. There is minimal risk of cross-contamination because no liquid handling or splashing happens during sample processing. With no clogs and fewer breakdowns, there are fewer disruptions to your workflow.
Easy-to-Use Interface Simplifies Your RNA or DNA Extraction Workflow
Touch the screen to start the process
The intuitive touch screen interface lets you easily set up your DNA or RNA extraction run. And the advanced administrator functions let you control required sample information and report archiving options.
Prepare the sample cartridges
Place prepared cartridges in the Maxwell® RSC. Press “Start” to purify 1–16 samples using the selected kit’s preprogrammed method. New kit methods are easy to install to expand your instrument capabilities.
Quantitate your purified sample
Complete your nucleic acid purification workflow with highly sensitive and specific fluorescence-based nucleic acid quantification using the Quantus™ Fluorometer with a simple add-and-read format, and receive all your sample data in one report. Easily archive your run reports and export the data for your lab notebook.
Integrated Quantus™ Fluorometer for quantitation
Following nucleic acid purification with the Maxwell® RSC, you can quickly and easily quantitate your sample using the included Quantus™ Fluorometer.
The Quantus™ Fluorometer is a dual-channel fluorometer that provides highly sensitive fluorescent detection in a compact, simple-to-use instrument. When used with the preprogrammed settings for Promega QuantiFluor® Dye Systems (QuantiFluor® dsDNA, RNA and ssDNA Systems), the Quantus™ Fluorometer can quickly quantitate nucleic acids. The sensitivity and broad dynamic range of the Quantus™ Fluorometer and QuantiFluor® Dyes allow you to complement your absorbance-based methods and quantify your target molecule over a wider range of concentrations.
The Quantus™ Fluorometer is equipped with two fluorescence channels for nucleic acid and protein quantitation:
Blue fluorescence channel:
Excitation 495nm shortpass (wavelengths up to 495nm), emission 510–580nm.
Red fluorescence channel:
Excitation 640nm shortpass (wavelengths up to 640nm), emission 660–720nm.
Quantitate Even Low-Level DNA SamplesAccurately
The sensitivity and broad dynamic range of the Quantus™ Fluorometer and QuantiFluor® Dyes allow you to complement your absorbance-based methods and quantify your target molecule over a wider range of concentrations.
Works With Multiple Sample Types
DNA Extraction
DNA purified with the Maxwell® RSC System is compatible with a wide range of downstream applications such as Sanger and next generation sequencing, arrays and digital PCR.
Maxwell® RSC Whole Blood DNA Kit »
Extracts DNA from larger sample sizes (up to 500µl) of whole blood without preprocessing
Maxwell® RSC Blood DNA Kit »
Extracts higher yields of DNA from up to 300µl of whole blood following Proteinase K treatment
Maxwell® RSC Buffy Coat DNA »
Extracts DNA from buffy coat from blood
Maxwell® RSC Genomic DNA Kit »
Extracts high-quality DNA from whole blood, buffy coat, bone marrow, buccal swabs, cells and tissue
Maxwell® RSC Buccal Swab DNA Kit »
Extracts DNA from buccal swab
Maxwell® RSC Genomic DNA Kit »
Extracts high-quality DNA from whole blood, buffy coat, bone marrow, buccal swabs, cells and tissue
Maxwell® RSC Fecal Microbiome DNA Kit »
Extracts DNA from human and mammalian feces.
Maxwell® RSC Cultured Cells DNA Kit »
Extracts DNA from up to 5x10⁶ mammalian tissue culture cells and 2x10⁹ bacterial cells
Maxwell® RSC Cell DNA Purification Kit »
Extracts DNA from samples containing less than 10,000 cells such as amniotic fluid, cerebral spinal fluid and cell supernatants
Maxwell® RSC Genomic DNA Kit »
Extracts high-quality DNA from whole blood, buffy coat, bone marrow, buccal swabs, cells and tissue
Maxwell® RSC DNA FFPE Kit »
Extracts DNA from formalin-fixed paraffin embedded (FFPE) tissue sections
Maxwell® FFPE Plus LEV DNA Purification Kits »
Extracts DNA from FFPE samples with comparable performance to the Maxwell® 16 DNA FFPE LEV Plus Kit
Maxwell® RSC Genomic DNA Kit »
Extracts high-quality DNA from whole blood, buffy coat, bone marrow, buccal swabs, cells and tissue
Maxwell® RSC Tissue DNA Kit »
Extracts DNA from 50mg of tissue
Maxwell® RSC Plant DNA Kit »
Extracts DNA from a range of plant sample types including soybean, corn and Arabidopsis
Maxwell® RSC PureFood GMO and Authentication Kit »
Extracts DNA from a wide range of food sample types including soybean, corn, canola, fish, beef and pork
Maxwell® RSC PureFood Pathogen Kit »
Extracts bacterial DNA from a wide range of food sample types for use in NGS, serotyping and identification of spoilage organisms
Maxwell® RSC Stabilized Saliva DNA Kit »
Extracts DNA from stabilized saliva tubes
Maxwell® RSC ccfDNA Plasma Kit »
Extracts ccfDNA from plasma
Maxwell® RSC Viral Total Nucleic Acid Purification Kit »
Extracts viral total nucleic acid (RNA and DNA) from serum, plasma and other samples
RNA Extraction
RNA purified with the Maxwell® RSC System is compatible with downstream applications, such as RT-PCR.
Maxwell® RSC simplyRNA Blood Kit »
Purifies total RNA from 2.5ml of fresh whole blood
Maxwell® RSC simplyRNA Cells Kit »
Purifies total RNA from fresh or frozen cells
Maxwell® RSC RNA FFPE Kit »
Extracts RNA from formalin-fixed paraffin embedded (FFPE) tissue sections
Maxwell® RSC Plant RNA Kit »
Extracts RNA from a range of plant sample types including soybean, corn and Arabidopsis
Maxwell® RSC simplyRNA Tissue Kit »
Purifies total RNA from up to 20mg of tissue
Maxwell® RSC miRNA Tissue Kit »
Purifies total RNA, including miRNA, from mammalian tissue samples
Maxwell® RSC Viral Total Nucleic Acid Purification Kit »
Extracts viral total nucleic acid (RNA and DNA) from serum, plasma and other samples
Maxwell® RSC miRNA Plasma and Serum Kit »
Purifies high-quality, amplifiable miRNA from plasma, serum or enriched exosomes
Instrument Specifications
Processing Time: 25–60 minutes
Number of Samples: Up to 16
Weight: 24.2lb (11kg)
Dimensions: 13W × 13.6D × 11.8H inches(330.2 × 345.2 × 299.7mm)
Power Requirements: 100–240VAC,50/60Hz, 2.5A
Fuse: 250VAC, 2.5A, low breaking capacity, time-lag fuse (AC250V, T2.5AL, 5 × 20mm)
UV Bulb: Average lifetime approximately 6,000 hours, length 135.9mm, diameter 16mm, 4W, 0.17A current, 29V, spectral peak F 253.7, UV output 0.9W
Instrument Standard Components
A. Maxwell® RSC Instrument
B. Tablet PC preloaded with Maxwell® RSC Application Software
C. USB Cable - Maxwell® RSC Instrument to Tablet PC
D. Power Cable for Maxwell® RSC Instrument
E. Power Cords for Tablet PC
F. Maxwell® RSC/CSC Deck Tray
G. Quantus™ Fluorometer and accessories
H. Tablet PC Holder
I. USB cable - Maxwell® RSC Instrument to Quantus™ Fluorometer
UV Bulb (installed)
Quick Start Guide
Setup Guide
Accessories Available Separately
Additional deck trays, plungers and an optional bar code reader are available for purchase separately.
Protocols
Complete Protocol
Specifications
Catalog Number:
SDS
Search for SDSCertificate of Analysis
Use Restrictions
For Research Use Only. Not for Use in Diagnostic Procedures.Storage Conditions
U.S. Pat. Nos. 7,721,947 and 7,891,549, European Pat. No. 2033144 and Japanese Pat. Nos. 5519276 and 5654519.
Resources
Articles
- Modified Protocol for Extracting RNA-free Plant DNA
- Comparing Two Automated Methods for Viral Total Nucleic Acid Purification
- Establishment of preanalytical conditions for microRNA profile analysis of clinical plasma samples
- Maxwell® RSC Blood DNA and RNA Purification Kits: A Comparison to QIAcube® Methods
- A Comparison of Methods for DNA and RNA Purification From Plant
- miRNA Purification from Plant Tissues: Corn, Soybean and Arabidopsis
- DNA Extraction from Fungi Environmental Field Samples
- Maxwell® RSC simplyRNA Tissue Kit: A Comparison to the QIAcube® Method
- Maxwell® RSC DNA and RNA FFPE Kits: A Comparison to QIAcube® Methods
Software and Firmware
Other Resources
Related Products
Similar Products
Maxwell® RSC DNA FFPE Kit
Extracts DNA from FFPE tissue samples using the Maxwell® RSC Instrument.
AS1450, ASB1450
Maxwell® RSC RNA FFPE Kit
Purifies RNA from FFPE tissue sections using the Maxwell® RSC Instrument.
AS1440
Maxwell® RSC Blood DNA Kit
Purifies DNA from whole blood samples using the Maxwell® RSC Instrument.
AS1400, ASB1400
Maxwell® RSC simplyRNA Blood Kit
Purifies RNA from 1–16 whole blood samples using a low elution volume and the Maxwell® RSC Instrument.
AS1380, ASB1380
Maxwell® RSC miRNA from Tissue or Plasma and Serum Kits
In combination with the Maxwell® RSC Instrument, the kit purifies high-quality total RNA with an enhanced miRNA enrichment.
AS1460, AS1680
Maxwell® RSC Whole Blood DNA Kit
Extracts DNA from whole blood samples using the Maxwell® RSC Instrument.
AS1520, ASB1520
Maxwell® RSC Plant RNA Kit
Extracts RNA from plant tissue samples using the Maxwell® RSC Instrument.
AS1500
Maxwell® RSC simplyRNA Cells Kit
Purifies RNA from cells using a low elution volume and the Maxwell® RSC Instrument.
AS1390
Frequently Used With
Maxwell® RSC Qualification Products
Installation Qualification (IQ) and Operational Qualification (OQ) products for the Maxwell® RSC Instrument.
SA1347, SA1348, SA1349
Maxwell® RSC Accessory Products
Deck trays and accessory products for the Maxwell® RSC Instrument.
SP6019, AS3200, AS1331, AS1670, AS6201, AS4017, Z3871
Maxwell® RSC Service and Support Products
Service and warranty products for the Maxwell® RSC Instrument.
SA1341, SA1342, SA1343, SA1346, SA1362, SA1363, SA1364, SA1365
QuantiFluor® ssDNA System
Fluorescent dye for sensitive quantitation of single-stranded DNA in solution.
E3190
