Expanding Applications of Bioluminescence Technology: Predictive Bioassays for TNFα Biologicals Potency and Dose-Standardization Studies
Sarah Shultz, Andrew Niles, Jey Cheng and Simon T.M. Allard
Promega Corporation
Publication Date: 2008
Promega Corporation
Publication Date: 2008
Abstract
Simple and predictive bioassays for potency and dose-standardization are still sought by the biopharmaceutical industry. Automatable, homogeneous bioassays are desirable because they can help to streamline this evaluative process. Implementing straightforward predictive automation-friendly bioassays as demonstrated in this article allows effective assessment of anti-TNFα and likely other biologicals for quality control. This article was reprinted in Promega Notes 100 with permission from Genetic Engineering News.
Promega Notes 100, 19–21.
This animation introduces the concept of reporter gene assays.
