Advancing Cellular Imaging with Enhanced Tagging Technologies

In the field of fluorescence microscopy, traditional fluorescent proteins have been instrumental in visualizing cellular processes, but they come with significant limitations. Issues such as photobleaching, poor signal-to-noise ratios and limited color options have often hindered the quality, reliability and multiplexing potential of imaging results. The HaloTag® system offers a robust solution by allowing researchers to fuse their protein of interest with the HaloTag® protein and pair it with the powerful Janelia Fluor® dyes that are available in a variety of colors. This versatile approach not only enhances imaging by forming a highly specific covalent bond but also opens a gateway for investigating protein function in various cellular contexts.

Learn how this innovative labeling approach addresses the challenges of traditional fluorescent proteins, such as photobleaching and low signal-to-noise ratios. The webinar will cover key super-resolution techniques, including Structured Illumination Microscopy (SIM), STORM, and STED, and their applications in both live and fixed specimen imaging. Gain valuable insights into how combining these techniques with Janelia Fluor® dyes can enhance imaging resolution, enabling more detailed cellular studies. Join us for an in-depth session exploring the latest advancements in super-resolution microscopy, with a focus on the Janelia Fluor®/ Halo Tag® system.