PPIF, peptidylprolyl isomerase F

PPIF, peptidylprolyl isomerase F

• The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]

• Gene Synonyms (peptidyl-prolyl cis-trans isomerase F, mitochondrial, PPIase F, cyclophilin 3, cyclophilin D, cyclophilin F, mitochondrial cyclophilin, peptidyl-prolyl cis-trans isomerase, mitochondrial, rotamase F, CYP3, CyP-M, Cyp-D, CypD,)
• NCBI Gene ID: 10105
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P30405
  UNIPROT ID#>>A0A024QZS4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

peptidylprolyl isomerase F interacts with:

• abl interactor 2
  ADP ribosylation factor interacting protein 2
  angiotensin II receptor associated protein
  apoptosis inducing factor mitochondria associated 3
  BTG3 associated nuclear protein
  cell death inducing DFFA like effector b
  CKLF like MARVEL transmembrane domain containing 5
  family with sequence similarity 25 member A
  family with sequence similarity 25 member C
  family with sequence similarity 25 member G
  FKBP prolyl isomerase 7
  glutathione S-transferase kappa 1
  histidine triad nucleotide binding protein 2
  leucine rich repeat kinase 2
  methylphosphate capping enzyme
  mitochondrial ribosomal protein L14
  mitochondrial ribosomal protein L53
  mitochondrial ribosome recycling factor
  mitochondrial rRNA methyltransferase 1
  M-phase specific PLK1 interacting protein
  NADH:ubiquinone oxidoreductase complex assembly factor 2
  NME1-NME2 readthrough
  nucleic acid binding protein 2
  pleckstrin homology domain containing A4
  SRA stem-loop interacting RNA binding protein
  SRP receptor subunit beta
  SURP and G-patch domain containing 1
  TBL1X receptor 1
  TPX2 microtubule nucleation factor
  translocase of inner mitochondrial membrane 44
  transport and golgi organization 2 homolog
  tRNA methyltransferase 61B
  ubiquitination factor E4B
  Yip1 interacting factor homolog A, membrane trafficking protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.