KLF2, Kruppel like factor 2

KLF2, Kruppel like factor 2

• This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is expressed early in mammalian development and is found in many different cell types. The protein acts to bind the CACCC box found in the promoter of target genes to activate their transcription. It plays a role in many processes during development and disease including adipogenesis, embryonic erythropoiesis, epithelial integrity, inflammation and t-cell viability. [provided by RefSeq, Mar 2017]

• Gene Synonyms (LKLF, Krueppel-like factor 2, Kruppel-like factor 2 (lung), Kruppel-like factor LKLF, lung Kruppel-like factor, lung Kruppel-like zinc finger transcription factor, lung krueppel-like factor,)
• NCBI Gene ID: 10365
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5W3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Kruppel like factor 2 interacts with:

• F-box and WD repeat domain containing 7
  GATA binding protein 5
  SMAD specific E3 ubiquitin protein ligase 1
  WW domain containing E3 ubiquitin protein ligase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.