PPP6R1, protein phosphatase 6 regulatory subunit 1

PPP6R1, protein phosphatase 6 regulatory subunit 1

• Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]

• Gene Synonyms (KIAA1115, PP6R1, SAP190, SAPS1, serine/threonine-protein phosphatase 6 regulatory subunit 1, SAPS domain family, member 1,)
• NCBI Gene ID: 22870
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UPN7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 6 regulatory subunit 1 interacts with:

• acyl-CoA dehydrogenase family member 11
  ankyrin repeat domain 28
  ankyrin repeat domain 28
  ankyrin repeat domain 44
  ankyrin repeat domain 52
  argonaute RISC component 1
  autophagy related 16 like 1
  carboxypeptidase A6
  CCR4-NOT transcription complex subunit 1
  CCR4-NOT transcription complex subunit 10
  centrosomal protein 44
  DISC1 scaffold protein
  DNA cross-link repair 1C
  egl-9 family hypoxia inducible factor 3
  F-box and leucine rich repeat protein 13
  forkhead box K1
  histone deacetylase 11
  hypoxia inducible factor 1 subunit alpha inhibitor
  IQ motif containing N
  limb development membrane protein 1 like
  MOB kinase activator 1A
  MOB kinase activator 1B
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  PNKD metallo-beta-lactamase domain containing
  protein phosphatase 6 regulatory subunit 3
  protein phosphatase 6, catalytic subunit
  receptor interacting serine/threonine kinase 4
  ring finger protein 123
  serine/threonine kinase 40
  SRP receptor subunit beta
  TANK binding kinase 1
  tRNA methyltransferase 2 homolog A
  ubiquitin specific peptidase 49
  unc-93 homolog B1, TLR signaling regulator

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