ERP44, endoplasmic reticulum protein 44

ERP44, endoplasmic reticulum protein 44

• This gene encodes a member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. It has an inferred N-terminal signal peptide, a catalytically active thioredoxin (TRX) domain, two TRX-like domains and a C-terminal ER-retention sequence. This protein functions as a pH-regulated chaperone of the secretory pathway and likely plays a role in protein quality control at the endoplasmic reticulum - Golgi interface. [provided by RefSeq, Dec 2016]

• Gene Synonyms (PDIA10, TXNDC4, endoplasmic reticulum resident protein 44, ER protein 44, endoplasmic reticulum resident protein 44 kDa, epididymis secretory sperm binding protein, protein disulfide isomerase family A, member 10, thioredoxin domain containing 4 (endoplasmic reticulum), thioredoxin domain-containing protein 4,)
• NCBI Gene ID: 23071
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BS26
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

endoplasmic reticulum protein 44 interacts with:

• BCL6 corepressor
  cell division cycle 73
  COP9 signalosome subunit 7B
  decapping mRNA 1B
  egl-9 family hypoxia inducible factor 3
  endoplasmic reticulum oxidoreductase 1 alpha
  endoplasmic reticulum oxidoreductase 1 beta
  ER degradation enhancing alpha-mannosidase like protein 3
  erythrocyte membrane protein band 4.1 like 4B
  fidgetin, microtubule severing factor
  G protein nucleolar 3 like
  inositol-trisphosphate 3-kinase C
  integrin alpha FG-GAP repeat containing 1
  isochorismatase domain containing 1
  leucyl-tRNA synthetase 1
  limb development membrane protein 1 like
  lysine methyltransferase 2C
  mex-3 RNA binding family member A
  mitoguardin 1
  NudC domain containing 1
  O-sialoglycoprotein endopeptidase
  phospholipase D family member 3
  plasmanylethanolamine desaturase 1
  pyridoxamine 5'-phosphate oxidase
  Ras association domain family member 5
  sulfatase modifying factor 1
  syntaxin binding protein 4
  ubiquitin conjugating enzyme E2 Q1
  ubiquitin family domain containing 1
  ubiquitin interaction motif containing 1
  ubiquitin specific peptidase 32
  ubiquitin specific peptidase 46
  zinc finger MYM-type containing 1
  zinc finger protein 777
  zinc finger protein, FOG family member 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.