EDEM3, ER degradation enhancing alpha-mannosidase like protein 3

EDEM3, ER degradation enhancing alpha-mannosidase like protein 3

• Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (ER degradation-enhancing alpha-mannosidase-like protein 3, ER degradation enhancer, mannosidase alpha-like 3, ER degradation-enhancing -mannosidase-like protein 3, ER degradation-enhancing alpha-mannosidase-like 3, alpha-1,2-mannosidase EDEM3, C1orf22,)
• NCBI Gene ID: 80267
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R931
  UNIPROT ID#>>Q9BZQ6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ER degradation enhancing alpha-mannosidase like protein 3 interacts with:

• STT3 oligosaccharyltransferase complex catalytic subunit B
  thioredoxin domain containing 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.