SEC11A, SEC11 homolog A, signal peptidase complex subunit

SEC11A, SEC11 homolog A, signal peptidase complex subunit

• This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Dec 2012]

• Gene Synonyms (signal peptidase complex catalytic subunit SEC11A, SEC11-like protein 1, SPase 18 kDa subunit, endopeptidase SP18, microsomal signal peptidase 18 kDa subunit, signal peptidase complex (18kD), signal peptidase complex 18, 1810012E07Rik, SEC11L1, SPC18, SPCS4A, sid2895,)
• NCBI Gene ID: 23478
• Species: Homo sapiens (Human)
• UNIPROT ID#>>H0YKT4
  UNIPROT ID#>>P67812
  UNIPROT ID#>>A0A024RC78
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SEC11 homolog A, signal peptidase complex subunit interacts with:

• ADAM metallopeptidase domain 33
  EvC ciliary complex subunit 2
  F-box protein 6
  limb development membrane protein 1 like
  nuclear protein 1, transcriptional regulator
  OTU deubiquitinase with linear linkage specificity like
  signal peptidase complex subunit 2 homolog (S. cerevisiae)
  solute carrier family 35 member F6
  tectonic family member 1
  tectonic family member 2
  tectonic family member 3
  transmembrane protein 17
  transmembrane protein 216
  transmembrane protein 67

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.