TCTN3, tectonic family member 3

TCTN3, tectonic family member 3

• This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012]

• Gene Synonyms (tectonic-3, C10orf61, JBTS18, OFD4, TECT3,)
• NCBI Gene ID: 26123
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6NUS6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tectonic family member 3 interacts with:

• 3-hydroxyacyl-CoA dehydratase 2
  3-hydroxyacyl-CoA dehydratase 3
  adiponectin receptor 2
  ALG6 alpha-1,3-glucosyltransferase
  ALG9 alpha-1,2-mannosyltransferase
  anoctamin 6
  ATPase 13A1
  B9 domain containing 2
  BRI3 binding protein
  carboxypeptidase A4
  CDGSH iron sulfur domain 2
  CDK5 regulatory subunit associated protein 1 like 1
  ceramide synthase 2
  choline phosphotransferase 1
  CLPTM1 like
  coiled-coil and C2 domain containing 2A
  coiled-coil domain containing 115
  coiled-coil domain containing 47
  cornichon family AMPA receptor auxiliary protein 4
  cytochrome b5 type B
  DEAD-box helicase 47
  DEAD-box helicase 54
  dehydrogenase/reductase 7
  DEP domain containing 1B
  derlin 1
  derlin 2
  DnaJ heat shock protein family (Hsp40) member B11
  DnaJ heat shock protein family (Hsp40) member C1
  DnaJ heat shock protein family (Hsp40) member C10
  DnaJ heat shock protein family (Hsp40) member C11
  dolichyldiphosphatase 1
  dpy-19 like C-mannosyltransferase 3
  ELOVL fatty acid elongase 1
  endoplasmic reticulum oxidoreductase 1 alpha
  endoplasmic reticulum oxidoreductase 1 beta
  ER membrane protein complex subunit 10
  ER membrane protein complex subunit 3
  ER membrane protein complex subunit 4
  ER membrane protein complex subunit 6
  ER membrane protein complex subunit 7
  ERGIC and golgi 2
  ERGIC and golgi 3
  fatty acid 2-hydroxylase
  F-box protein 6
  G protein-coupled receptor 89A
  glutathione S-transferase kappa 1
  glycerol-3-phosphate acyltransferase 3
  glycerol-3-phosphate acyltransferase 4
  golgi transport 1B
  GRAM domain containing 1A
  histocompatibility minor 13
  hydroxysteroid 17-beta dehydrogenase 12
  hydroxysteroid dehydrogenase like 2
  IKBKB interacting protein
  jagunal homolog 1
  junctophilin 1
  keratinocyte associated protein 2
  keratinocyte proline rich protein
  leucine rich repeat containing 59
  limb development membrane protein 1 like
  lipase maturation factor 2
  lunapark, ER junction formation factor
  lysocardiolipin acyltransferase 1
  magnesium transporter 1
  membrane bound O-acyltransferase domain containing 2
  membrane bound O-acyltransferase domain containing 7
  membrane magnesium transporter 1
  motile sperm domain containing 2
  NAD(P) dependent steroid dehydrogenase-like
  NDC1 transmembrane nucleoporin
  nicalin
  NUS1 dehydrodolichyl diphosphate synthase subunit
  ORMDL sphingolipid biosynthesis regulator 2
  ORMDL sphingolipid biosynthesis regulator 3
  oxysterol binding protein like 8
  PEDS1-UBE2V1 readthrough
  phosphatidylinositol glycan anchor biosynthesis class S
  phosphatidylinositol glycan anchor biosynthesis class T
  phosphatidylinositol glycan anchor biosynthesis class U
  phosphatidylserine synthase 2
  protein O-mannose kinase
  RAB, member of RAS oncogene family like 3
  Rac GTPase activating protein 1
  receptor accessory protein 2
  receptor accessory protein 4
  RFT1 homolog
  rhomboid domain containing 2
  secretion associated Ras related GTPase 1A
  selenoprotein I
  serpin family A member 12
  signal peptidase complex subunit 1
  signal peptidase complex subunit 3
  solute carrier family 30 member 5
  solute carrier family 30 member 6
  solute carrier family 30 member 7
  solute carrier family 35 member B4
  solute carrier family 38 member 2
  solute carrier family 38 member 9
  solute carrier family 39 member 10
  sphingomyelin phosphodiesterase 4
  SRP receptor subunit beta
  stearoyl-CoA desaturase 5
  sterile alpha motif domain containing 8
  STT3 oligosaccharyltransferase complex catalytic subunit B
  SUMO specific peptidase 3
  tectonic family member 1
  tectonic family member 2
  terminal nucleotidyltransferase 4B
  thioesterase superfamily member 6
  thioredoxin domain containing 5
  thioredoxin related transmembrane protein 1
  thioredoxin related transmembrane protein 3
  TLC domain containing 1
  TLC domain containing 2
  torsin 1A interacting protein 2
  transducin beta like 2
  transient receptor potential cation channel subfamily M member 7
  transmembrane 9 superfamily member 3
  transmembrane and coiled-coil domains 1
  transmembrane anterior posterior transformation 1
  transmembrane O-mannosyltransferase targeting cadherins 3
  transmembrane p24 trafficking protein 9
  transmembrane protein 109
  transmembrane protein 120B
  transmembrane protein 184C
  transmembrane protein 199
  transmembrane protein 209
  transmembrane protein 214
  transmembrane protein 33
  transmembrane protein 35B
  transmembrane protein 38B
  transmembrane protein 41A
  transmembrane protein 41B
  transmembrane protein 43
  ubiquitin conjugating enzyme E2 J1
  UDP-glucose glycoprotein glucosyltransferase 1
  unc-93 homolog B1, TLR signaling regulator
  vacuolar ATPase assembly factor VMA21
  vacuole membrane protein 1
  VANGL planar cell polarity 1
  VANGL planar cell polarity protein 1
  vezatin, adherens junctions transmembrane protein
  vitamin K epoxide reductase complex subunit 1 like 1
  Wnt ligand secretion mediator
  Yip1 interacting factor homolog B, membrane trafficking protein
  zinc finger protein 644

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.