MYCBP, MYC binding protein

MYCBP, MYC binding protein

• The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011]

• Gene Synonyms (C-Myc-binding protein, associate of myc-1, c-myc binding protein, AMY-1,)
• NCBI Gene ID: 26292
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99417
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MYC binding protein interacts with:

• A kinase (PRKA) anchor protein 8
  argonaute RISC component 4
  cilia and flagella associated protein 91
  copine 2
  copine 4
  dipeptidyl peptidase 7
  dispatched RND transporter family member 3
  egl-9 family hypoxia inducible factor 3
  eukaryotic translation initiation factor 5A like 1
  eukaryotic translation initiation factor 5A2
  HEXIM P-TEFb complex subunit 2
  kinetochore-localized astrin/SPAG5 binding
  MYCBP associated protein
  OTU deubiquitinase 4
  replication initiator 1
  Rho guanine nucleotide exchange factor 40
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 31
  VRK serine/threonine kinase 3
  zinc finger and BTB domain containing 38

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.