RBMXL2, RBMX like 2

RBMXL2, RBMX like 2

• This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq, Jul 2008]

• Gene Synonyms (RNA-binding motif protein, X-linked-like-2, RNA binding motif protein, X-linked like 2, heterogeneous nuclear ribonucleoprotein G T, hnRNP G-T, testes-specific heterogenous nuclear ribonucleoprotein G-T, testis-specific heterogeneous nuclear ribonucleoprotein G-T, HNRNPG-T, HNRNPGT, HNRPGT,)
• NCBI Gene ID: 27288
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75526
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RBMX like 2 interacts with:

• bromodomain containing 7
  cullin associated and neddylation dissociated 1
  ferredoxin-fold anticodon binding domain containing 1
  La ribonucleoprotein 7, transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.