BRD7, bromodomain containing 7

BRD7, bromodomain containing 7

• This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

• Gene Synonyms (bromodomain-containing protein 7, 75 kDa bromodomain protein, protein CELTIX-1, BP75, CELTIX1, NAG4,)
• NCBI Gene ID: 29117
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NPI1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

bromodomain containing 7 interacts with:

• 3-hydroxyacyl-CoA dehydratase 3
  acidic nuclear phosphoprotein 32 family member E
  actin beta like 2
  activating signal cointegrator 1 complex subunit 2
  acylglycerol kinase
  anaphase promoting complex subunit 7
  ATPase family AAA domain containing 3A
  ATPase family AAA domain containing 3B
  AT-rich interaction domain 2
  bromodomain containing 7
  BTB domain containing 2
  cell division cycle 73
  chromodomain helicase DNA binding protein 7
  chromosome 1 open reading frame 35
  chromosome transmission fidelity factor 18
  CST telomere replication complex component 1
  CWF19 like cell cycle control factor 1
  cyclin dependent kinase 11A
  cytochrome P450 family 27 subfamily C member 1
  DEAD-box helicase 24
  DEAD-box helicase 41
  DEAD-box helicase 47
  DEAD-box helicase 49
  DEAD-box helicase 54
  DEAD-box helicase 55
  DEAD-box helicase 56
  DEAH-box helicase 33
  DEAH-box helicase 36
  DEAH-box helicase 37
  DEAH-box helicase 40
  DExD-box helicase 50
  DExH-box helicase 57
  DnaJ heat shock protein family (Hsp40) member B11
  eEF1A lysine and N-terminal methyltransferase
  epithelial splicing regulatory protein 2
  erythrocyte membrane protein band 4.1 like 5
  exoribonuclease 1
  family with sequence similarity 91 member A1
  family with sequence similarity 98 member B
  FAST kinase domains 5
  fatty acyl-CoA reductase 1
  formin like 2
  FtsJ RNA 2'-O-methyltransferase 3
  G protein nucleolar 2
  G protein nucleolar 3 like
  G protein-coupled receptor associated sorting protein 2
  GDP-mannose pyrophosphorylase A
  glutamate rich WD repeat containing 1
  G-patch domain containing 4
  H3 clustered histone 14
  H3 clustered histone 15
  hdc homolog, cell cycle regulator
  HECT and RLD domain containing E3 ubiquitin protein ligase 5
  heterogeneous nuclear ribonucleoprotein A3
  IKBKB interacting protein
  IQ motif containing GTPase activating protein 3
  La ribonucleoprotein 1B
  leucine rich repeat containing 47
  leucine rich repeat containing 59
  leukocyte receptor cluster member 8
  ligand dependent nuclear receptor interacting factor 1
  LIM domain and actin binding 1
  LTV1 ribosome biogenesis factor
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  LUC7 like 3 pre-mRNA splicing factor
  MAP7 domain containing 1
  metadherin
  mitochondrial calcium uptake 2
  mitochondrial ribosomal protein S9
  N-acetyltransferase 10
  NOC3 like DNA replication regulator
  NOP2/Sun RNA methyltransferase 2
  NOP2/Sun RNA methyltransferase 5
  NOP58 ribonucleoprotein
  nuclear assembly factor 1 ribonucleoprotein
  nucleolar complex associated 4 homolog
  nucleolar protein interacting with the FHA domain of MKI67
  nucleolar protein with MIF4G domain 1
  paraspeckle component 1
  peter pan homolog
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  PHD finger protein 10
  PHD finger protein 6
  pleckstrin homology and FYVE domain containing 2
  polybromo 1
  polypyrimidine tract binding protein 2
  pre-mRNA processing factor 40 homolog A
  protein kinase N3
  pseudouridine synthase 1
  regulator of chromosome condensation 2
  replication timing regulatory factor 1
  Rho guanine nucleotide exchange factor 39
  ribosomal protein L7 like 1
  ribosome production factor 2 homolog
  ring finger protein 146
  RNA 2',3'-cyclic phosphate and 5'-OH ligase
  RNA binding motif protein 25
  RNA binding motif protein X-linked 2
  RNA transcription, translation and transport factor
  SH3 and PX domains 2B
  sideroflexin 4
  spermatid perinuclear RNA binding protein
  spermatogenesis associated 5
  spermatogenesis associated 5 like 1
  STN1 subunit of CST complex
  THO complex 2
  TNFAIP3 interacting protein 2
  transcription elongation factor, mitochondrial
  translocase of inner mitochondrial membrane 50
  tRNA methyltransferase 1 like
  tRNA methyltransferase 6
  tRNA methyltransferase 61A
  TSR1 ribosome maturation factor
  tubulin alpha 1c
  tubulin alpha 4b
  tubulin beta 1 class VI
  tubulin beta 6 class V
  tubulin beta class I
  ubiquitin protein ligase E3 component n-recognin 1
  UPF3B regulator of nonsense mediated mRNA decay
  UTP18 small subunit processome component
  UTP4 small subunit processome component
  VPS53 subunit of GARP complex
  WD repeat domain 12
  WD repeat domain 76
  YTH domain containing 2
  YTH N6-methyladenosine RNA binding protein 2
  zinc finger C3H1-type containing
  zinc finger CCCH-type containing 15
  zinc finger CCCH-type containing, antiviral 1
  zinc finger CCHC-type containing 10

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.