SENP1, SUMO specific peptidase 1

SENP1, SUMO specific peptidase 1

• This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

• Gene Synonyms (sentrin-specific protease 1, SUMO1/sentrin specific peptidase 1, SUMO1/sentrin specific protease 1, sentrin/SUMO-specific protease SENP1, SuPr-2,)
• NCBI Gene ID: 29843
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9P0U3
  UNIPROT ID#>>Q6N001
  UNIPROT ID#>>Q7Z3G1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SUMO specific peptidase 1 interacts with:

• ADP ribosylation factor like GTPase 11
  centromere protein E
  egl-9 family hypoxia inducible factor 3
  HAUS augmin-like complex, subunit 1
  ninein
  nucleoporin 107
  nucleoporin 107
  nucleoporin 43
  nucleus accumbens associated 1
  OTU deubiquitinase with linear linkage specificity like
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  PHD finger protein 12
  potassium channel tetramerisation domain containing 5
  receptor interacting serine/threonine kinase 4
  scavenger receptor class A member 3
  sirtuin 6
  SUMO specific peptidase 1
  tRNA methyltransferase 1
  ubiquitin specific peptidase 28
  zinc finger protein 420

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.