NIN, ninein

NIN, ninein

• This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ninein, glycogen synthase kinase 3 beta-interacting protein, hNinein, ninein (GSK3B interacting protein), ninein centrosomal protein, SCKL7,)
• NCBI Gene ID: 51199
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N4C6
  UNIPROT ID#>>Q5XUU0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ninein interacts with:

• 5'-3' exoribonuclease 1
  actin related protein 10
  agrin
  angiomotin
  anillin actin binding protein
  ANKHD1-EIF4EBP3 readthrough
  ARFGEF family member 3
  ATPase H+ transporting V1 subunit H
  aurora kinase A and ninein interacting protein
  BLOC-1 related complex subunit 6
  BTB domain and CNC homolog 2
  calmodulin regulated spectrin associated protein 1
  calmodulin regulated spectrin associated protein family member 3
  capping protein regulator and myosin 1 linker 2
  centromere protein J
  centrosomal protein 128
  centrosomal protein 170B
  centrosomal protein 192
  centrosomal protein 20
  centrosomal protein 290
  centrosomal protein 295
  centrosomal protein 55
  centrosomal protein 63
  centrosomal protein 85 like
  centrosomal protein 95
  centrosomal protein 97
  centrosome and spindle pole associated protein 1
  chromosome 1 open reading frame 198
  ciliogenesis and planar polarity effector 1
  cingulin like 1
  coiled-coil alpha-helical rod protein 1
  coiled-coil and C2 domain containing 1A
  coiled-coil domain containing 138
  coiled-coil domain containing 14
  coiled-coil domain containing 57
  coiled-coil domain containing 66
  coiled-coil domain containing 68
  coiled-coil domain containing 77
  coiled-coil domain containing 85C
  cytokine induced apoptosis inhibitor 1
  DEAH-box helicase 35
  DEAH-box helicase 40
  diaphanous related formin 3
  DOT1 like histone lysine methyltransferase
  egl-9 family hypoxia inducible factor 3
  eukaryotic translation initiation factor 4E nuclear import factor 1
  exocyst complex component 4
  extended synaptotagmin 2
  family with sequence similarity 184 member A
  family with sequence similarity 83 member B
  family with sequence similarity 83 member G
  family with sequence similarity 83 member H
  fused in sarcoma
  G2 and S-phase expressed 1
  G-patch domain containing 1
  HAUS augmin like complex subunit 1
  HAUS augmin like complex subunit 2
  HAUS augmin like complex subunit 3
  HAUS augmin like complex subunit 4
  HAUS augmin like complex subunit 6
  HAUS augmin like complex subunit 7
  HAUS augmin like complex subunit 8
  intermediate filament family orphan 2
  intraflagellar transport 46
  intraflagellar transport 74
  KIAA1217
  KIAA1671
  kinesin family member 7
  kinetochore localized astrin (SPAG5) binding protein
  kizuna centrosomal protein
  L3MBTL histone methyl-lysine binding protein 2
  lebercilin LCA5
  leucine rich repeat and coiled-coil centrosomal protein 1
  MAP7 domain containing 3
  meiosis specific with coiled-coil domain
  MIA SH3 domain ER export factor 3
  mindbomb E3 ubiquitin protein ligase 1
  misato mitochondrial distribution and morphology regulator 1
  mitochondrial calcium uniporter
  mitochondrial poly(A) polymerase
  mitochondrial ribosomal protein L41
  mitotic spindle organizing protein 2B
  NCK associated protein 5 like
  NEDD1 gamma-tubulin ring complex targeting factor
  ninein
  NODAL modulator 2
  nudE neurodevelopment protein 1
  PCI domain containing 2
  pleckstrin homology and RhoGEF domain containing G1
  POC5 centriolar protein
  proline and serine rich 3
  pseudouridine synthase 1
  RAD50 interactor 1
  Rho GTPase activating protein 21
  ring finger protein 135
  RNA transcription, translation and transport factor
  SAS-6 centriolar assembly protein
  signal induced proliferation associated 1 like 2
  sodium channel and clathrin linker 1
  SPC24 component of NDC80 kinetochore complex
  SSX family member 2 interacting protein
  sterile alpha motif domain containing 4B
  synaptonemal complex central element protein 3
  taxilin alpha
  taxilin gamma
  TBC1 domain family member 31
  t-complex 10 like
  testis expressed 9
  tetratricopeptide repeat domain 26
  tetratricopeptide repeat domain 30A
  tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
  transmembrane protein 165
  trichoplein keratin filament binding
  tubulin alpha 1c
  tubulin beta 6 class V
  ubiquitin specific peptidase 54
  unc-45 myosin chaperone A
  valosin containing protein interacting protein 1
  WD repeat domain 61
  WD repeat domain 83
  YTH N6-methyladenosine RNA binding protein 2
  zinc finger protein 331
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.