UFM1, ubiquitin fold modifier 1

UFM1, ubiquitin fold modifier 1

• UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M; MIM 603173) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Dec 2008]

• Gene Synonyms (ubiquitin-fold modifier 1, BM-002, C13orf20, HLD14,)
• NCBI Gene ID: 51569
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P61960
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin fold modifier 1 interacts with:

• CDK5 regulatory subunit associated protein 3
  diablo IAP-binding mitochondrial protein
  elongation factor like GTPase 1
  inhibitor of CDK, cyclin A1 interacting protein 1
  musashi RNA binding protein 2
  NPL4 homolog, ubiquitin recognition factor
  O-sialoglycoprotein endopeptidase
  pantothenate kinase 4 (inactive)
  photoreceptor cilium actin regulator
  potassium channel tetramerization domain containing 21
  riboflavin kinase
  ring finger and CCCH-type domains 2
  TP53 regulating kinase
  ubiquitin conjugating enzyme E2 D4 (putative)
  ubiquitin conjugating enzyme E2 W
  ubiquitin like modifier activating enzyme 5
  UFM1 specific ligase 1
  zinc finger FYVE-type containing 19

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.